C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: PIF1 5'-to-3' DNA helicase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000333425 PIF1-002 ENSG00000140451 9606 - 15:64815632-64825668 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartOvaryPlacentaENST00000333425
Transcript ID Brain Heart Ovary Placenta
ENST00000333425 0.097±0.00 0.083±0.00 0.298±0.00 0.261±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RY CIL_0007RY_0001 VISTA 15:64785331-65389080

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000002 IEA mitochondrial genome maintenance
GO:0000287 IDA magnesium ion binding
GO:0000723 IEA telomere maintenance
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0003678 IEA DNA helicase activity
GO:0004386 IEA helicase activity
GO:0005524 IDA:IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0006200 IDA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0010521 IEA telomerase inhibitor activity
GO:0017116 IDA single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0032204 IDA regulation of telomere maintenance
GO:0032211 IEA negative regulation of telomere maintenance via telomerase
GO:0032508 IEA DNA duplex unwinding
GO:0033682 IDA ATP-dependent 5'-3' DNA/RNA helicase activity
GO:0042162 IDA telomeric DNA binding
GO:0043141 IDA ATP-dependent 5'-3' DNA helicase activity
GO:0051880 IEA G-quadruplex DNA binding
GO:0051974 IDA negative regulation of telomerase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000131483 Pif1-004 protein_coding Mus_musculus 0 1853
ENSMUST00000134538 Pif1-002 protein_coding Mus_musculus 0 1853
ENSMUST00000047099 Pif1-001 protein_coding Mus_musculus 0 1853
ENSMUST00000154970 Pif1-003 nonsense_mediated_decay Mus_musculus 0 1103
ENSMUST00000152885 Pif1-006 retained_intron Mus_musculus 0 481
ENSMUST00000152529 Pif1-005 retained_intron Mus_musculus 0 479

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