C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: metadherin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000336273 MTDH-001 ENSG00000147649 9606 + 8:97644179-97728770 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336273
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336273 8.080±0.00 8.122±0.00 3.175±0.00 5.899±0.43 9.045±0.44 7.986±0.22 4.103±1.04 8.170±0.60 8.210±0.21 7.427±1.67 5.043±3.26 10.946±2.49 3.569±1.07 7.064±1.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L2 CIL_0001L2_0001 CGP 8:97273474-97728770
CIL_0001KW CIL_0001KW_0001 CGP 8:97644179-97853013

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0003713 IMP transcription coactivator activity
GO:0003725 IDA double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005923 ISS tight junction
GO:0010508 IDA positive regulation of autophagy
GO:0016021 IEA integral component of membrane
GO:0016324 ISS apical plasma membrane
GO:0016604 IDA nuclear body
GO:0031663 IMP lipopolysaccharide-mediated signaling pathway
GO:0043066 IDA negative regulation of apoptotic process
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044822 IDA poly(A) RNA binding
GO:0045766 IDA positive regulation of angiogenesis
GO:0046581 ISS intercellular canaliculus
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051059 IPI NF-kappaB binding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0070830 IEA tight junction assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022865 Mtdh-001 protein_coding Mus_musculus 0 4222
ENSMUST00000171711 Mtdh-004 processed_transcript Mus_musculus 0 1251
ENSMUST00000163333 Mtdh-005 protein_coding Mus_musculus 0 1046
ENSMUST00000163697 Mtdh-003 retained_intron Mus_musculus 0 994
ENSMUST00000170050 Mtdh-008 protein_coding Mus_musculus 0 896
ENSMUST00000172082 Mtdh-002 retained_intron Mus_musculus 0 848
ENSMUST00000169905 Mtdh-006 protein_coding Mus_musculus 0 837
ENSMUST00000172083 Mtdh-007 processed_transcript Mus_musculus 0 802
ENSMUST00000168991 Mtdh-010 nonsense_mediated_decay Mus_musculus 0 680
ENSMUST00000170553 Mtdh-009 protein_coding Mus_musculus 0 536
ENSMUST00000179332 5730455P16Rik-201 protein_coding Mus_musculus 0.000002 60
ENSMUST00000103225 5730455P16Rik-001 protein_coding Mus_musculus 0.000002 60

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