C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: patatin-like phospholipase domain containing 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000336615 PNPLA2-001 ENSG00000177666 9606 + 11:818902-825573 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336615
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336615 307.125±0.00 2.199±0.00 8.328±6.94 222.592±218.45 23.615±17.68 46.776±44.17 32.478±0.00 4.615±0.00 3.521±0.00 7.728±0.00 23.082±20.00 35.663±0.28 28.220±5.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EM CIL_0003EM_0001 CGP 11:809647-825573
CIL_0003EN CIL_0003EN_0001 CGP 11:818902-831991

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004806 ISS triglyceride lipase activity
GO:0005515 IEA protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005811 IDA lipid particle
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0008152 IEA metabolic process
GO:0010891 IDA negative regulation of sequestering of triglyceride
GO:0010898 IDA positive regulation of triglyceride catabolic process
GO:0016021 IEA integral component of membrane
GO:0019433 IEA triglyceride catabolic process
GO:0019915 IEA lipid storage
GO:0034389 IEA lipid particle organization
GO:0036155 TAS acylglycerol acyl-chain remodeling
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000164016 Pnpla2-001 protein_coding Mus_musculus 0 1373
ENSMUST00000026583 Pnpla2-002 nonsense_mediated_decay Mus_musculus 0 1144
ENSMUST00000064151 Pnpla2-005 protein_coding Mus_musculus 0 856
ENSMUST00000164924 Pnpla2-003 nonsense_mediated_decay Mus_musculus 0 743
ENSMUST00000169723 Pnpla2-008 nonsense_mediated_decay Mus_musculus 0 658
ENSMUST00000169665 Pnpla2-006 protein_coding Mus_musculus 0 531
ENSMUST00000165487 Pnpla2-007 protein_coding Mus_musculus 0 505

Loading