C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate decarboxylase 1 (brain, 67kDa)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000344257 GAD1-002 ENSG00000128683 9606 + 2:170816912-170842759 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastENST00000344257
Transcript ID Adrenal Breast
ENST00000344257 0.219±0.00 0.336±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SB CIL_0003SB_0002 CGP 2:170783786-170861151
CIL_0003SC CIL_0003SC_0002 CGP 2:170813213-170967129

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004351 IDA glutamate decarboxylase activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005886 TAS plasma membrane
GO:0006538 TAS glutamate catabolic process
GO:0006540 TAS glutamate decarboxylation to succinate
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0012506 NAS vesicle membrane
GO:0016831 IEA carboxy-lyase activity
GO:0018352 TAS protein-pyridoxal-5-phosphate linkage
GO:0019752 IEA carboxylic acid metabolic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0042136 IEA neurotransmitter biosynthetic process
GO:0061202 TAS clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000148210 Gad1-003 protein_coding Mus_musculus 0 1116
ENSMUST00000130998 Gad1-004 protein_coding Mus_musculus 0 1083
ENSMUST00000130604 Gad1-002 nonsense_mediated_decay Mus_musculus 0 1044
ENSMUST00000094934 Gad1-001 protein_coding Mus_musculus 0 900
ENSMUST00000123330 Gad1-008 protein_coding Mus_musculus 0 850
ENSMUST00000155979 Gad1-005 retained_intron Mus_musculus 0 771
ENSMUST00000140478 Gad1-006 processed_transcript Mus_musculus 0 747

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