C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: runt-related transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000344691 RUNX1-001 ENSG00000159216 9606 - 21:34787801-34888690 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344691
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344691 5.159±0.00 3.003±0.00 0.765±0.00 0.694±0.58 3.110±0.56 1.304±0.15 0.448±0.22 0.263±0.15 0.374±0.08 4.448±1.93 0.874±0.58 3.550±1.09 3.041±0.68 0.574±0.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZS CIL_0008ZS_0001 VISTA 21:34243666-34847364
CIL_00094R CIL_00094R_0001 VISTA 21:34258399-34859715
CIL_00078F CIL_00078F_0001 CGP 21:34669389-36004667

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000975 IDA regulatory region DNA binding
GO:0003677 IDA:IEA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 IDA transcription factor binding
GO:0030097 TAS hemopoiesis
GO:0030099 IDA myeloid cell differentiation
GO:0030853 IMP negative regulation of granulocyte differentiation
GO:0030854 IMP positive regulation of granulocyte differentiation
GO:0042803 IDA protein homodimerization activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048935 TAS peripheral nervous system neuron development
GO:0071425 TAS hematopoietic stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168195 Runx1-004 protein_coding Mus_musculus 0 2030
ENSMUST00000023673 Runx1-001 protein_coding Mus_musculus 0 1827
ENSMUST00000113956 Runx1-003 protein_coding Mus_musculus 0 905
ENSMUST00000189126 Runx1-005 retained_intron Mus_musculus 0 582
ENSMUST00000119564 Runx3-002 protein_coding Mus_musculus 0 383
ENSMUST00000056977 Runx3-001 protein_coding Mus_musculus 0 383
ENSDART00000130697 RUNX1 (2 of 2)-201 protein_coding Danio_rerio 0 333
ENSMUST00000156478 Runx3-003 retained_intron Mus_musculus 0 274
ENSMUST00000186296 Runx1-002 protein_coding Mus_musculus 0 239

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