C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tumor protein p63
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354600 TP63-004 ENSG00000073282 9606 + 3:189789660-189897268 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000354600
Transcript ID Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000354600 0.011±0.00 2.347±0.00 0.018±0.00 0.066±0.00 0.511±0.51 0.749±0.00 1.544±0.60 2.444±1.07 1.399±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Y5 CIL_0003Y5_0002 CGP 3:188947214-189897279
CIL_000933 CIL_000933_0001 VISTA 3:189215860-189816512
CIL_0000DP CIL_0000DP_0001 CGP 3:189631416-190122437

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IBA chromatin
GO:0000790 IDA nuclear chromatin
GO:0002039 IBA p53 binding
GO:0003677 NAS DNA binding
GO:0003682 IBA chromatin binding
GO:0003684 IBA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IBA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005667 IBA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 IBA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006915 TAS apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007219 IEA Notch signaling pathway
GO:0010165 IBA response to X-ray
GO:0010332 IBA response to gamma radiation
GO:0010482 ISS regulation of epidermal cell division
GO:0030425 IBA dendrite
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0034644 IBA cellular response to UV
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042802 IPI identical protein binding
GO:0043523 IBA regulation of neuron apoptotic process
GO:0043565 IBA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0050699 IPI WW domain binding
GO:0051262 IEA protein tetramerization
GO:0051289 IPI protein homotetramerization
GO:0061436 ISS establishment of skin barrier
GO:1902808 IMP positive regulation of cell cycle G1/S phase transition
GO:2000271 IDA positive regulation of fibroblast apoptotic process
GO:2000773 IMP negative regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040231 Trp63-001 protein_coding Mus_musculus 0 2924
ENSMUST00000115306 Trp63-002 protein_coding Mus_musculus 0 2846
ENSMUST00000115310 Trp63-003 protein_coding Mus_musculus 0 2741
ENSMUST00000065523 Trp63-201 protein_coding Mus_musculus 0 1812
ENSMUST00000115305 Trp63-006 protein_coding Mus_musculus 0 1580
ENSMUST00000115308 Trp63-202 protein_coding Mus_musculus 0 1319
ENSMUST00000115304 Trp63-005 protein_coding Mus_musculus 0 1317
ENSMUST00000115307 Trp63-004 protein_coding Mus_musculus 0 363

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