C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: calmodulin 1 (phosphorylase kinase, delta)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000356978 CALM1-001 ENSG00000198668 9606 + 14:90396983-90408261 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356978
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356978 89.996±0.00 62.554±0.00 20.006±0.00 287.951±22.69 75.346±50.06 76.414±42.41 43.377±21.00 35.982±20.64 32.672±14.66 47.537±17.47 61.235±40.03 36.010±14.68 37.011±2.68 62.027±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001U8 CIL_0001U8_0001 CGP 14:90267856-90408261
CIL_0005CA CIL_0005CA_0001 CGP 14:90396502-90816479

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000922 IDA spindle pole
GO:0001975 IEA response to amphetamine
GO:0002027 IMP regulation of heart rate
GO:0002576 TAS platelet degranulation
GO:0005509 ISS:IEA calcium ion binding
GO:0005513 IMP detection of calcium ion
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005876 IDA spindle microtubule
GO:0005886 TAS plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0005980 TAS glycogen catabolic process
GO:0006006 TAS glucose metabolic process
GO:0006936 TAS muscle contraction
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007190 IEA activation of adenylate cyclase activity
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0007603 TAS phototransduction, visible light
GO:0008179 IEA adenylate cyclase binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010800 TAS positive regulation of peptidyl-threonine phosphorylation
GO:0010801 TAS negative regulation of peptidyl-threonine phosphorylation
GO:0010880 IDA regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 IC regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0019722 IEA calcium-mediated signaling
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0021762 IEP substantia nigra development
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0030017 IDA sarcomere
GO:0030168 TAS platelet activation
GO:0030234 IEA enzyme regulator activity
GO:0030235 IEA nitric-oxide synthase regulator activity
GO:0030426 IEA growth cone
GO:0030801 IDA positive regulation of cyclic nucleotide metabolic process
GO:0031432 IPI titin binding
GO:0031800 IEA type 3 metabotropic glutamate receptor binding
GO:0031954 TAS positive regulation of protein autophosphorylation
GO:0031982 IDA vesicle
GO:0031996 IPI thioesterase binding
GO:0031997 IPI N-terminal myristoylation domain binding
GO:0032465 IMP regulation of cytokinesis
GO:0032516 IDA positive regulation of phosphoprotein phosphatase activity
GO:0034704 IDA calcium channel complex
GO:0035307 IDA positive regulation of protein dephosphorylation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043274 IPI phospholipase binding
GO:0043539 TAS protein serine/threonine kinase activator activity
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044325 IPI ion channel binding
GO:0045087 TAS innate immune response
GO:0046209 TAS nitric oxide metabolic process
GO:0047485 IEA protein N-terminus binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048306 IEA calcium-dependent protein binding
GO:0050998 IEA nitric-oxide synthase binding
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0051343 IDA positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051412 IEA response to corticosterone
GO:0051592 IDA response to calcium ion
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060314 IEA regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315 ISS negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 IDA positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0071902 TAS positive regulation of protein serine/threonine kinase activity
GO:0072542 IDA protein phosphatase activator activity
GO:1901841 IEA regulation of high voltage-gated calcium channel activity
GO:1901844 IC regulation of cell communication by electrical coupling involved in cardiac conduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110082 Calm1-001 protein_coding Mus_musculus 0 1674
ENSMUST00000001204 Calm1-002 protein_coding Mus_musculus 0 1520
ENSMUST00000127300 Calm1-004 retained_intron Mus_musculus 0 508
ENSMUST00000153524 Calm1-003 retained_intron Mus_musculus 0 357

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