C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Ca++ transporting, plasma membrane 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000357681 ATP2B4-001 ENSG00000058668 9606 + 1:203626561-203744081 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357681
Transcript ID Adipose Adrenal Bladder Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357681 19.950±0.00 2.555±0.00 3.235±0.00 26.882±16.95 1.625±0.00 3.358±1.26 4.311±1.02 16.961±5.65 0.685±0.09 12.192±10.68 12.100±2.02 3.796±1.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096T CIL_00096T_0001 VISTA 1:203391843-203993678

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005388 IMP:IEA calcium-transporting ATPase activity
GO:0005515 IPI protein binding
GO:0005516 IDA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005901 TAS caveola
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006874 IDA cellular calcium ion homeostasis
GO:0007596 TAS blood coagulation
GO:0008152 IEA metabolic process
GO:0010751 IDA negative regulation of nitric oxide mediated signal transduction
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017080 ISS sodium channel regulator activity
GO:0030018 IDA Z disc
GO:0030315 IDA T-tubule
GO:0030346 IDA protein phosphatase 2B binding
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0034220 TAS ion transmembrane transport
GO:0036487 IDA nitric-oxide synthase inhibitor activity
GO:0042383 IEA sarcolemma
GO:0043234 ISS protein complex
GO:0045019 IDA negative regulation of nitric oxide biosynthetic process
GO:0046872 IEA metal ion binding
GO:0050998 IPI nitric-oxide synthase binding
GO:0051001 IDA negative regulation of nitric-oxide synthase activity
GO:0051599 IMP response to hydrostatic pressure
GO:0055074 IC calcium ion homeostasis
GO:0055085 TAS transmembrane transport
GO:0070588 IMP:IEA calcium ion transmembrane transport
GO:0070885 IDA negative regulation of calcineurin-NFAT signaling cascade
GO:0071872 IDA cellular response to epinephrine stimulus
GO:0097110 ISS scaffold protein binding
GO:0098703 IC calcium ion import across plasma membrane
GO:0098736 IDA negative regulation of the force of heart contraction
GO:1900082 IDA negative regulation of arginine catabolic process
GO:1901205 IDA negative regulation of adrenergic receptor signaling pathway involved in heart process
GO:1902083 NAS negative regulation of peptidyl-cysteine S-nitrosylation
GO:1902305 IC regulation of sodium ion transmembrane transport
GO:1903243 IMP negative regulation of cardiac muscle hypertrophy in response to stress
GO:1903249 IDA negative regulation of citrulline biosynthetic process
GO:2000481 IDA positive regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000143567 Atp2b4-001 protein_coding Mus_musculus 0 4250
ENSMUST00000165602 Atp2b4-202 protein_coding Mus_musculus 0 3893
ENSMUST00000048953 Atp2b4-201 protein_coding Mus_musculus 0 3783
ENSMUST00000125659 Atp2b4-003 protein_coding Mus_musculus 0 3768
ENSMUST00000112264 Atp2b4-002 protein_coding Mus_musculus 0 3459
ENSMUST00000088429 Atp2b3-001 protein_coding Mus_musculus 0 1472
ENSMUST00000114479 Atp2b3-002 protein_coding Mus_musculus 0 1454
ENSMUST00000033744 Atp2b3-003 protein_coding Mus_musculus 0 1450
ENSMUST00000101044 Atp2b2-003 protein_coding Mus_musculus 0 1315
ENSMUST00000101045 Atp2b2-001 protein_coding Mus_musculus 0 1315
ENSMUST00000089003 Atp2b2-004 protein_coding Mus_musculus 0 1315
ENSMUST00000152831 Atp2b2-002 nonsense_mediated_decay Mus_musculus 0 1308
ENSMUST00000020107 Atp2b1-201 protein_coding Mus_musculus 0 1229
ENSMUST00000128692 Atp2b4-005 processed_transcript Mus_musculus 0 368

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