Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	glutamate receptor, metabotropic 8
ENST00000358373	GRM8-002	ENSG00000179603	9606	-	7:126438615-127252381	protein_coding

Expression Patterns

Transcript ID	Brain	Breast	Liver	Ovary	Testis
ENST00000358373	0.858±0.00	0.195±0.00	0.452±0.00	0.137±0.00	0.204±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0001OL	CIL_0001OL_0001	CGP	7:124822386-127253294

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001642	IBA	group III metabotropic glutamate receptor activity
GO:0004930	IMP:IEA	G-protein coupled receptor activity
GO:0005886	TAS	plasma membrane
GO:0005887	IBA	integral component of plasma membrane
GO:0007186	IEA	G-protein coupled receptor signaling pathway
GO:0007196	IMP	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007601	TAS	visual perception
GO:0007608	IEA	sensory perception of smell
GO:0008066	IMP	glutamate receptor activity
GO:0016021	IEA	integral component of membrane
GO:0030818	IDA	negative regulation of cAMP biosynthetic process
GO:0042734	IBA	presynaptic membrane
GO:0051966	IBA	regulation of synaptic transmission, glutamatergic

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000115323	Grm8-001	protein_coding	Mus_musculus	0	4998
ENSMUST00000115324	Grm8-201	protein_coding	Mus_musculus	0	4492
ENSMUST00000090512	Grm8-002	protein_coding	Mus_musculus	0	3838
ENSMUST00000131897	Grm8-003	protein_coding	Mus_musculus	0	1541
ENSMUST00000146727	Grm8-004	processed_transcript	Mus_musculus	0	1295
ENSDART00000112940	GRM8 (1 of 2)-201	protein_coding	Danio_rerio	0	1114
ENSDART00000155949	GRM8 (1 of 2)-001	protein_coding	Danio_rerio	0	1114
ENSMUST00000132755	Grm8-005	protein_coding	Mus_musculus	0	379

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