C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hydroxysteroid (11-beta) dehydrogenase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367027 HSD11B1-001 ENSG00000117594 9606 + 1:209704846-209734950 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367027
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367027 1.608±0.00 0.382±0.00 0.092±0.00 2.959±0.07 5.182±3.01 1.192±0.31 0.590±0.17 113.230±0.00 9.659±8.63 4.813±3.06 0.305±0.08 10.040±11.77 21.261±11.79 1.781±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089N CIL_00089N_0001 VISTA 1:209189712-209790617
CIL_0007ZL CIL_0007ZL_0001 VISTA 1:209515705-210116479

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003845 TAS 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0008152 IEA metabolic process
GO:0008202 TAS steroid metabolic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070524 IEA 11-beta-hydroxysteroid dehydrogenase (NADP+) activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000016338 Hsd11b1-002 protein_coding Mus_musculus 0 776
ENSMUST00000161737 Hsd11b1-001 protein_coding Mus_musculus 0 693
ENSMUST00000160929 Hsd11b1-003 protein_coding Mus_musculus 0 592
ENSMUST00000159644 Hsd11b1-004 protein_coding Mus_musculus 0 588
ENSMUST00000162842 Hsd11b1-005 protein_coding Mus_musculus 0 337
ENSMUST00000161406 Hsd11b1-006 protein_coding Mus_musculus 1e-32 145

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