C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: connective tissue growth factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367976 CTGF-001 ENSG00000118523 9606 - 6:131948176-131951373 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367976
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367976 57.579±0.00 65.494±0.00 9.481±0.00 9.944±8.31 65.073±27.43 37.698±33.50 21.785±20.54 131.246±128.79 5.012±1.84 41.713±32.05 7.638±1.44 65.366±53.20 147.760±78.72 47.405±41.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097U CIL_00097U_0001 VISTA 6:131762456-132364269

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001502 IEA cartilage condensation
GO:0001503 IEA ossification
GO:0001525 IEA angiogenesis
GO:0001558 IEA regulation of cell growth
GO:0001894 IEA tissue homeostasis
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001968 IEA fibronectin binding
GO:0005178 IEA integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 TAS:IEA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0005794 IDA Golgi apparatus
GO:0005801 IEA cis-Golgi network
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0005938 IEA cell cortex
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008543 IEA fibroblast growth factor receptor signaling pathway
GO:0008544 TAS epidermis development
GO:0009611 TAS response to wounding
GO:0009749 IEA response to glucose
GO:0010260 IEA organ senescence
GO:0010467 TAS gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0010942 IEA positive regulation of cell death
GO:0014070 IEA response to organic cyclic compound
GO:0016477 IEA cell migration
GO:0030154 IEA cell differentiation
GO:0030324 IEA lung development
GO:0032330 IEA regulation of chondrocyte differentiation
GO:0032355 IEA response to estradiol
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0034059 IEA response to anoxia
GO:0035556 IEA intracellular signal transduction
GO:0035988 IEA chondrocyte proliferation
GO:0043200 IEA response to amino acid
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043434 IEA response to peptide hormone
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045597 IDA positive regulation of cell differentiation
GO:0046330 IDA positive regulation of JNK cascade
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050867 IEA positive regulation of cell activation
GO:0051385 IEA response to mineralocorticoid
GO:0051496 IDA positive regulation of stress fiber assembly
GO:0060401 IEA cytosolic calcium ion transport
GO:0060452 IEA positive regulation of cardiac muscle contraction
GO:0060548 IEA negative regulation of cell death
GO:0061448 IEA connective tissue development
GO:0070278 IEA extracellular matrix constituent secretion
GO:0070318 IEA positive regulation of G0 to G1 transition
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0070542 IEA response to fatty acid
GO:0071897 IEA DNA biosynthetic process
GO:0072593 IEA reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020171 Ctgf-001 protein_coding Mus_musculus 0 1642
ENSMUST00000176228 Ctgf-003 protein_coding Mus_musculus 0 891
ENSMUST00000129142 Ctgf-002 protein_coding Mus_musculus 0 259

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