C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FYN proto-oncogene, Src family tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368667 FYN-014 ENSG00000010810 9606 - 6:111661282-111793886 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000368667
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000368667 4.919±0.00 2.691±0.00 4.768±0.00 2.910±0.00 4.442±0.00 1.276±0.42 1.338±0.00 2.180±1.27 5.258±0.00 15.919±0.00 10.687±0.00 4.351±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000954 CIL_000954_0001 VISTA 6:111250485-111855465

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001948 IPI glycoprotein binding
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 NAS non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005768 IDA endosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006468 NAS:IEA protein phosphorylation
GO:0006816 NAS calcium ion transport
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0007612 TAS learning
GO:0007631 TAS feeding behavior
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016032 TAS viral process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030168 TAS platelet activation
GO:0031295 TAS T cell costimulation
GO:0035556 TAS intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS innate immune response
GO:0045121 IDA membrane raft
GO:0046872 IEA metal ion binding
GO:0046875 IPI ephrin receptor binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050690 TAS regulation of defense response to virus by virus
GO:0050852 IDA T cell receptor signaling pathway
GO:0050900 TAS leukocyte migration
GO:0070851 IPI growth factor receptor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000099967 Fyn-002 protein_coding Mus_musculus 0 3011
ENSMUST00000126486 Fyn-003 protein_coding Mus_musculus 0 1604
ENSMUST00000063091 Fyn-001 protein_coding Mus_musculus 0 1604
ENSMUST00000136659 Fyn-008 protein_coding Mus_musculus 0 1598
ENSMUST00000146287 Fyn-005 protein_coding Mus_musculus 0 1480
ENSMUST00000135242 Fyn-004 protein_coding Mus_musculus 0 1480
ENSDART00000150232 fyna-001 protein_coding Danio_rerio 0 1168
ENSDART00000023320 fyna-201 protein_coding Danio_rerio 0 1153
ENSMUST00000148152 Fyn-006 protein_coding Mus_musculus 0 601
ENSDART00000046414 fyna-202 protein_coding Danio_rerio 0 551
ENSMUST00000123205 Fyn-009 processed_transcript Mus_musculus 0 374
ENSMUST00000157009 Fyn-007 protein_coding Mus_musculus 0 261

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