C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 2, group E, member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368983 NR2E1-002 ENSG00000112333 9606 + 6:108168023-108188802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLiverLungOvaryPlacentaTestisENST00000368983
Transcript ID Adipose Adrenal Brain Breast Colon Liver Lung Ovary Placenta Testis
ENST00000368983 0.005±0.00 0.005±0.00 0.652±0.38 0.040±0.00 0.010±0.00 0.013±0.00 0.004±0.00 0.074±0.04 0.030±0.01 0.033±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KA CIL_0007KA_0001 UCNEbase 6:107632412-108443377
CIL_0008G4 CIL_0008G4_0001 VISTA 6:107814126-108415302
CIL_0009BP CIL_0009BP_0001 VISTA 6:107816039-108417248

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001662 IEA behavioral fear response
GO:0002118 IEA aggressive behavior
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007399 TAS nervous system development
GO:0007420 IEA brain development
GO:0007601 IEA visual perception
GO:0008270 IEA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008347 IEA glial cell migration
GO:0010467 TAS gene expression
GO:0019899 IEA enzyme binding
GO:0021542 IEA dentate gyrus development
GO:0021764 IEA amygdala development
GO:0021772 IEA olfactory bulb development
GO:0021819 IEA layer formation in cerebral cortex
GO:0021872 IEA forebrain generation of neurons
GO:0021895 IEA cerebral cortex neuron differentiation
GO:0021960 IEA anterior commissure morphogenesis
GO:0021987 IEA cerebral cortex development
GO:0030198 IEA extracellular matrix organization
GO:0035019 IEA somatic stem cell maintenance
GO:0035176 IEA social behavior
GO:0042826 IEA histone deacetylase binding
GO:0043010 IEA camera-type eye development
GO:0043066 IEA negative regulation of apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045165 IEA cell fate commitment
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045766 IEA positive regulation of angiogenesis
GO:0045787 IEA positive regulation of cell cycle
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048712 IEA negative regulation of astrocyte differentiation
GO:0048814 IEA regulation of dendrite morphogenesis
GO:0051128 IEA regulation of cellular component organization
GO:0060041 IEA retina development in camera-type eye
GO:0060164 IEA regulation of timing of neuron differentiation
GO:0060291 IEA long-term synaptic potentiation
GO:0090049 IEA regulation of cell migration involved in sprouting angiogenesis
GO:2000178 IEA negative regulation of neural precursor cell proliferation
GO:2000179 IEA positive regulation of neural precursor cell proliferation
GO:2000648 IEA positive regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019938 Nr2e1-001 protein_coding Mus_musculus 0 1725
ENSMUST00000105498 Nr2e1-002 protein_coding Mus_musculus 0 785
ENSMUST00000126848 Nr2e1-003 protein_coding Mus_musculus 0 688
ENSMUST00000143891 Nr2e1-004 protein_coding Mus_musculus 0 481

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