C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: runt-related transcription factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000371436 RUNX2-004 ENSG00000124813 9606 + 6:45328727-45547393 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainENST00000371436
Transcript ID Bladder Brain
ENST00000371436 0.222±0.00 0.486±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00028U CIL_00028U_0002 CGP 6:44387525-45377953
CIL_00028T CIL_00028T_0002 CGP 6:44809317-45664349
CIL_0007Z9 CIL_0007Z9_0001 VISTA 6:45132802-45734411
CIL_00082L CIL_00082L_0001 VISTA 6:45237622-45839555
CIL_00008A CIL_00008A_0003 CGP 6:45328157-46080395

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 ISS nuclear chromatin
GO:0001503 TAS ossification
GO:0001649 TAS osteoblast differentiation
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0010467 TAS gene expression
GO:0030509 ISS BMP signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0071773 ISS cellular response to BMP stimulus
GO:1901522 ISS positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000162629 Runx2-011 protein_coding Mus_musculus 0 2307
ENSMUST00000162373 Runx2-012 protein_coding Mus_musculus 0 2224
ENSMUST00000113571 Runx2-201 protein_coding Mus_musculus 0 1439
ENSMUST00000160673 Runx2-001 protein_coding Mus_musculus 0 1439
ENSMUST00000159943 Runx2-003 protein_coding Mus_musculus 0 1439
ENSMUST00000113572 Runx2-002 protein_coding Mus_musculus 0 1356
ENSMUST00000113568 Runx2-004 nonsense_mediated_decay Mus_musculus 0 885
ENSMUST00000162878 Runx2-009 protein_coding Mus_musculus 0 874
ENSMUST00000162816 Runx2-008 nonsense_mediated_decay Mus_musculus 0 813
ENSMUST00000162130 Runx2-010 protein_coding Mus_musculus 0 560
ENSMUST00000160672 Runx2-006 nonsense_mediated_decay Mus_musculus 0 342
ENSMUST00000160199 Runx2-014 protein_coding Mus_musculus 0 340
ENSMUST00000119564 Runx3-002 protein_coding Mus_musculus 0 327
ENSMUST00000056977 Runx3-001 protein_coding Mus_musculus 0 327
ENSMUST00000156478 Runx3-003 retained_intron Mus_musculus 0 243

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