C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: bromodomain containing 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000371835 BRD4-002 ENSG00000141867 9606 - 19:15247047-15280451 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonKidneyLiverMuscleOvaryPlacentaENST00000371835
Transcript ID Breast Colon Kidney Liver Muscle Ovary Placenta
ENST00000371835 0.748±0.00 0.945±0.00 1.131±0.00 2.970±2.45 0.693±0.00 7.271±6.27 12.385±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DW CIL_0004DW_0002 CGP 19:15226919-15332545
CIL_00043N CIL_00043N_0001 CGP 19:15235519-15379798

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000083 IMP regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000794 IDA condensed nuclear chromosome
GO:0002039 IDA p53 binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005694 IDA chromosome
GO:0005737 IDA cytoplasm
GO:0006338 IDA chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0010971 IMP positive regulation of G2/M transition of mitotic cell cycle
GO:0016032 IEA viral process
GO:0032968 IMP positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050727 IDA regulation of inflammatory response
GO:0070577 IDA lysine-acetylated histone binding
GO:1901407 IDA regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2000002 IMP negative regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120276 Brd4-005 protein_coding Mus_musculus 0 3371
ENSMUST00000114475 Brd4-202 protein_coding Mus_musculus 0 3288
ENSMUST00000119123 Brd4-004 protein_coding Mus_musculus 0 2828
ENSMUST00000121285 Brd4-003 protein_coding Mus_musculus 0 2826
ENSMUST00000003726 Brd4-201 protein_coding Mus_musculus 0 2815
ENSMUST00000127893 Brd4-001 protein_coding Mus_musculus 0 2289
ENSMUST00000125899 Brd4-002 nonsense_mediated_decay Mus_musculus 0 1498

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