C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polo-like kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372201 PLK3-001 ENSG00000173846 9606 + 1:44800225-44805990 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372201
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372201 3.368±0.00 4.087±0.00 0.857±0.00 2.607±0.00 2.338±1.18 0.905±0.05 1.010±0.00 1.630±1.15 0.493±0.03 6.354±4.67 1.448±0.00 5.893±2.96 6.716±2.12 1.410±0.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093U CIL_00093U_0001 VISTA 1:44224152-44825477

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000302 IDA response to reactive oxygen species
GO:0002039 IDA p53 binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005795 IDA Golgi stack
GO:0005813 IDA centrosome
GO:0006468 IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0006970 IDA response to osmotic stress
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007093 TAS mitotic cell cycle checkpoint
GO:0007113 TAS endomitotic cell cycle
GO:0009314 IDA response to radiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030425 IEA dendrite
GO:0031122 IMP cytoplasmic microtubule organization
GO:0032465 IMP regulation of cytokinesis
GO:0043025 IEA neuronal cell body
GO:0043066 IDA negative regulation of apoptotic process
GO:0043491 ISS protein kinase B signaling
GO:0044819 ISS mitotic G1/S transition checkpoint
GO:0051302 IDA regulation of cell division
GO:0090166 IDA Golgi disassembly
GO:0090316 IMP positive regulation of intracellular protein transport
GO:2000777 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000076859 Plk3-001 protein_coding Mus_musculus 0 2663
ENSMUST00000126135 Plk3-002 processed_transcript Mus_musculus 0 1818
ENSMUST00000147730 Plk3-003 protein_coding Mus_musculus 0 1249
ENSMUST00000062206 Tctex1d4-001 protein_coding Mus_musculus 4e-20 104

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