C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cathepsin A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372459 CTSA-012 ENSG00000064601 9606 + 20:45891376-45898786 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartKidneyLiverLungMuscleOvaryENST00000372459
Transcript ID Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENST00000372459 33.525±0.00 17.093±0.00 34.142±0.00 98.454±0.00 34.843±0.00 40.149±0.00 31.219±0.00 54.155±15.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000RY CIL_0000RY_0001 CGP 20:45886489-45891287
CIL_0006GL CIL_0006GL_0001 CGP 20:45888625-45898820
CIL_0006IQ CIL_0006IQ_0002 CGP 20:45890144-45912155

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004180 TAS carboxypeptidase activity
GO:0004185 IEA serine-type carboxypeptidase activity
GO:0005634 IDA nucleus
GO:0005764 NAS lysosome
GO:0005783 TAS endoplasmic reticulum
GO:0006508 IEA proteolysis
GO:0006665 TAS sphingolipid metabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0006886 TAS intracellular protein transport
GO:0008047 TAS enzyme activator activity
GO:0016020 IDA membrane
GO:0043085 TAS positive regulation of catalytic activity
GO:0043202 TAS lysosomal lumen
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000017904 Ctsa-201 protein_coding Mus_musculus 0 1528
ENSMUST00000103092 Ctsa-001 protein_coding Mus_musculus 0 1528
ENSMUST00000103093 Ctsa-011 protein_coding Mus_musculus 0 1528
ENSMUST00000133077 Ctsa-005 retained_intron Mus_musculus 0 784
ENSMUST00000127650 Ctsa-002 protein_coding Mus_musculus 0 719
ENSMUST00000152721 Ctsa-013 protein_coding Mus_musculus 0 706
ENSMUST00000143293 Ctsa-007 processed_transcript Mus_musculus 0 580
ENSMUST00000128596 Ctsa-008 retained_intron Mus_musculus 0 484
ENSMUST00000143780 Ctsa-004 protein_coding Mus_musculus 0 429
ENSMUST00000155061 Ctsa-012 retained_intron Mus_musculus 0 344
ENSMUST00000144580 Ctsa-017 retained_intron Mus_musculus 0 281
ENSMUST00000130959 Ctsa-006 retained_intron Mus_musculus 0 209

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