C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FERM, RhoGEF and pleckstrin domain protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373287 FARP2-002 ENSG00000006607 9606 + 2:241356297-241466030 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LungTestisENST00000373287
Transcript ID Lung Testis
ENST00000373287 4.994±0.00 16.423±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JL CIL_0002JL_0001 CGP 2:241315100-241494841
CIL_0004UB CIL_0004UB_0002 CGP 2:241356243-241509730

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0007155 ISS cell adhesion
GO:0007411 TAS axon guidance
GO:0008092 IEA cytoskeletal protein binding
GO:0016322 IDA neuron remodeling
GO:0016601 IDA Rac protein signal transduction
GO:0019898 IEA extrinsic component of membrane
GO:0030316 ISS osteoclast differentiation
GO:0030676 ISS Rac guanyl-nucleotide exchange factor activity
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0033623 ISS regulation of integrin activation
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0071526 ISS semaphorin-plexin signaling pathway
GO:0071800 ISS podosome assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120301 Farp2-001 protein_coding Mus_musculus 0 1694
ENSMUST00000122402 Farp2-002 protein_coding Mus_musculus 0 1284

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