C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histone deacetylase 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373573 HDAC8-001 ENSG00000147099 9606 - X:72329516-72573103 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLungOvaryPlacentaTestisENST00000373573
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Lung Ovary Placenta Testis
ENST00000373573 1.896±0.00 0.938±0.00 2.499±0.18 0.979±0.00 3.033±0.00 1.717±0.00 0.464±0.00 2.526±1.37 2.228±1.13 0.983±0.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006RM CIL_0006RM_0001 CGP X:72301638-72573103
CIL_0006RW CIL_0006RW_0001 CGP X:72329516-72714319

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000228 TAS nuclear chromosome
GO:0000278 TAS mitotic cell cycle
GO:0004407 IEA:TAS histone deacetylase activity
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006333 TAS chromatin assembly or disassembly
GO:0006351 IEA transcription, DNA-templated
GO:0007062 IMP sister chromatid cohesion
GO:0008134 TAS transcription factor binding
GO:0016568 TAS chromatin modification
GO:0016575 IEA histone deacetylation
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046872 IEA metal ion binding
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0071922 IMP regulation of cohesin localization to chromatin
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087916 Hdac8-001 protein_coding Mus_musculus 0 1995
ENSMUST00000137785 Hdac8-002 processed_transcript Mus_musculus 0 1122
ENSMUST00000148481 Hdac8-003 processed_transcript Mus_musculus 0 992
ENSMUST00000154872 Hdac8-004 nonsense_mediated_decay Mus_musculus 0 710
ENSMUST00000154024 Hdac8-005 retained_intron Mus_musculus 0 398

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