C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal protein S6 kinase, 90kDa, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374168 RPS6KA1-001 ENSG00000117676 9606 + 1:26529767-26575025 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000374168
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000374168 2.927±0.00 4.917±0.00 3.013±0.00 2.546±0.15 3.719±1.74 1.467±0.00 6.181±5.79 14.696±0.00 6.804±8.19 4.114±1.18 2.858±0.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T4 CIL_0007T4_0001 VISTA 1:26423129-27024414

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004674 IEA:IDA protein serine/threonine kinase activity
GO:0004712 IDA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030307 TAS positive regulation of cell growth
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043555 TAS regulation of translation in response to stress
GO:0043620 TAS regulation of DNA-templated transcription in response to stress
GO:0045087 TAS innate immune response
GO:0045597 TAS positive regulation of cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade
GO:2000491 IMP positive regulation of hepatic stellate cell activation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105894 Rps6ka1-001 protein_coding Mus_musculus 0 3103
ENSMUST00000168974 Rps6ka1-003 protein_coding Mus_musculus 0 2822
ENSMUST00000157067 Rps6ka1-006 protein_coding Mus_musculus 0 2820
ENSMUST00000137486 Rps6ka1-004 protein_coding Mus_musculus 0 2817
ENSMUST00000174481 Rps6ka1-008 protein_coding Mus_musculus 0 2641
ENSMUST00000003741 Rps6ka1-002 protein_coding Mus_musculus 0 1871
ENSDART00000044378 rps6ka1-001 protein_coding Danio_rerio 0 1269
ENSDART00000129273 rps6ka1-004 protein_coding Danio_rerio 0 1269
ENSMUST00000024575 Rps6ka2-201 protein_coding Mus_musculus 0 1168
ENSMUST00000173989 Rps6ka1-007 retained_intron Mus_musculus 0 966
ENSMUST00000129636 Rps6ka1-005 retained_intron Mus_musculus 0 377

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