C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, non-receptor type 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374541 PTPN3-001 ENSG00000070159 9606 - 9:109375700-109498306 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverMuscleOvaryPlacentaTestisENST00000374541
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Muscle Ovary Placenta Testis
ENST00000374541 0.758±0.00 1.105±0.00 3.346±0.00 0.335±0.00 1.401±0.56 0.490±0.00 8.032±0.00 4.498±4.32 2.255±0.82 1.785±2.06 1.292±0.72 1.484±0.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IY CIL_0001IY_0001 CGP 9:109171975-109498313
CIL_0001GE CIL_0001GE_0001 CGP 9:109375466-109946703

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001784 IPI phosphotyrosine binding
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006470 IDA:IEA protein dephosphorylation
GO:0008092 IEA cytoskeletal protein binding
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0017080 IDA sodium channel regulator activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0051045 IMP negative regulation of membrane protein ectodomain proteolysis
GO:0051117 IPI ATPase binding
GO:0097421 IEA liver regeneration
GO:0098902 IDA regulation of membrane depolarization during action potential
GO:2000649 IDA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000075637 Ptpn3-001 protein_coding Mus_musculus 0 3217
ENSMUST00000153926 Ptpn3-003 protein_coding Mus_musculus 0 880
ENSMUST00000150445 Ptpn3-006 processed_transcript Mus_musculus 0 250
ENSMUST00000130900 Ptpn3-002 protein_coding Mus_musculus 0 195
ENSMUST00000151964 Ptpn3-005 protein_coding Mus_musculus 3e-30 139
ENSMUST00000061093 Slc30a10-201 protein_coding Mus_musculus 0.00000002 68

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