C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class I, E
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376630 HLA-E-001 ENSG00000204592 9606 + 6:30489467-30494205 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376630
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376630 694.468±0.00 379.523±0.00 12.843±0.00 57.533±47.21 184.080±125.07 162.077±127.13 53.174±33.64 118.233±74.19 77.201±33.16 1000.711±896.71 44.881±32.38 149.384±69.25 433.421±155.14 88.583±57.59

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IEA protein binding
GO:0006955 IEA immune response
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102678 H2-T23-001 protein_coding Mus_musculus 0 689
ENSMUST00000174250 H2-K2-001 unprocessed_pseudogene Mus_musculus 0 673
ENSMUST00000097335 Gm8909-201 protein_coding Mus_musculus 0 669
ENSMUST00000040467 Gm8909-001 protein_coding Mus_musculus 0 669
ENSMUST00000173353 Gm8909-002 protein_coding Mus_musculus 0 669
ENSMUST00000076256 H2-Q7-201 protein_coding Mus_musculus 0 667
ENSMUST00000025181 H2-K1-001 protein_coding Mus_musculus 0 662
ENSMUST00000114311 H2-K1-002 retained_intron Mus_musculus 0 662
ENSMUST00000172912 H2-K1-003 protein_coding Mus_musculus 0 662
ENSMUST00000071951 H2-Q7-001 protein_coding Mus_musculus 0 656
ENSMUST00000172538 C920025E04Rik-001 unprocessed_pseudogene Mus_musculus 0 651
ENSMUST00000078205 H2-Q7-202 protein_coding Mus_musculus 0 649
ENSMUST00000172979 H2-Q5-001 polymorphic_pseudogene Mus_musculus 0 647
ENSMUST00000068291 H2-Q10-201 protein_coding Mus_musculus 0 643
ENSMUST00000174525 H2-Q10-001 protein_coding Mus_musculus 0 643
ENSMUST00000074806 H2-Q2-001 protein_coding Mus_musculus 0 640
ENSMUST00000172785 H2-D1-001 protein_coding Mus_musculus 0 638
ENSMUST00000081435 H2-Q4-001 protein_coding Mus_musculus 0 623
ENSMUST00000113879 H2-Q6-201 protein_coding Mus_musculus 0 608
ENSMUST00000174699 H2-Q6-001 protein_coding Mus_musculus 0 608
ENSMUST00000073208 H2-Q1-001 protein_coding Mus_musculus 0 575
ENSMUST00000105041 H2-Q1-002 protein_coding Mus_musculus 0 575
ENSMUST00000173075 H2-K1-010 protein_coding Mus_musculus 0 540
ENSMUST00000173080 H2-Bl-201 protein_coding Mus_musculus 0 527
ENSMUST00000173625 Gm8909-004 processed_transcript Mus_musculus 0 414
ENSMUST00000113742 Gm11127-001 protein_coding Mus_musculus 0 394
ENSMUST00000174345 Gm17782-001 unprocessed_pseudogene Mus_musculus 0 390
ENSMUST00000173975 H2-Q4-002 retained_intron Mus_musculus 0 387
ENSMUST00000176712 H2-M5-002 protein_coding Mus_musculus 0 368
ENSMUST00000176784 H2-M5-005 protein_coding Mus_musculus 0 368
ENSMUST00000169189 H2-M5-001 protein_coding Mus_musculus 0 368
ENSMUST00000172994 H2-Q1-003 retained_intron Mus_musculus 0 363
ENSMUST00000046131 Gm7030-201 protein_coding Mus_musculus 0 355
ENSMUST00000173322 Gm7030-001 protein_coding Mus_musculus 0 355
ENSMUST00000172968 Gm7030-202 protein_coding Mus_musculus 0 351
ENSMUST00000173096 Gm8835-001 unprocessed_pseudogene Mus_musculus 0 346
ENSMUST00000185087 H2-Bl-005 nonsense_mediated_decay Mus_musculus 0 346
ENSMUST00000174778 Gm10499-001 retained_intron Mus_musculus 0 344
ENSMUST00000145260 H2-M5-003 retained_intron Mus_musculus 0 339
ENSMUST00000174839 H2-T23-002 retained_intron Mus_musculus 0 333
ENSMUST00000038580 H2-M3-001 protein_coding Mus_musculus 0 333
ENSMUST00000174161 H2-T23-003 retained_intron Mus_musculus 0 331
ENSMUST00000166442 H2-T10-201 protein_coding Mus_musculus 0 322
ENSMUST00000174382 H2-T10-003 polymorphic_pseudogene Mus_musculus 0 322
ENSMUST00000174625 H2-T10-004 retained_intron Mus_musculus 0 322
ENSMUST00000173809 Gm8815-001 unprocessed_pseudogene Mus_musculus 0 316
ENSMUST00000077960 H2-T22-002 protein_coding Mus_musculus 0 311
ENSMUST00000080015 H2-T22-001 protein_coding Mus_musculus 0 311
ENSMUST00000173280 H2-T22-005 nonsense_mediated_decay Mus_musculus 0 311
ENSMUST00000174693 Gm8909-003 processed_transcript Mus_musculus 0 309
ENSMUST00000058801 H2-T22-003 protein_coding Mus_musculus 0 307
ENSMUST00000172633 H2-T22-004 retained_intron Mus_musculus 0 307
ENSMUST00000173317 H2-K1-009 retained_intron Mus_musculus 0 305
ENSMUST00000087189 H2-K1-005 protein_coding Mus_musculus 0 305
ENSMUST00000174325 H2-D1-005 retained_intron Mus_musculus 0 302
ENSMUST00000171139 H2-M2-002 protein_coding Mus_musculus 0 302
ENSMUST00000016427 H2-M2-001 protein_coding Mus_musculus 0 302
ENSMUST00000185167 H2-Bl-002 nonsense_mediated_decay Mus_musculus 0 300
ENSMUST00000184850 H2-Bl-006 retained_intron Mus_musculus 0 300
ENSMUST00000173133 H2-T3-006 nonsense_mediated_decay Mus_musculus 0 298
ENSMUST00000102675 H2-T3-001 protein_coding Mus_musculus 0 298
ENSMUST00000173435 H2-T3-007 retained_intron Mus_musculus 0 291
ENSMUST00000173602 H2-K1-004 retained_intron Mus_musculus 0 291
ENSMUST00000174589 H2-Q10-002 retained_intron Mus_musculus 0 289
ENSMUST00000173016 H2-Q7-002 retained_intron Mus_musculus 0 283
ENSMUST00000173788 H2-Q7-003 retained_intron Mus_musculus 0 283
ENSMUST00000095300 H2-T3-003 nonsense_mediated_decay Mus_musculus 0 270
ENSMUST00000174101 H2-T3-002 nonsense_mediated_decay Mus_musculus 0 270
ENSMUST00000172663 H2-T3-008 nonsense_mediated_decay Mus_musculus 0 270
ENSMUST00000173629 H2-T3-009 nonsense_mediated_decay Mus_musculus 0 270
ENSMUST00000173577 H2-T3-004 retained_intron Mus_musculus 0 270
ENSMUST00000025312 H2-T3-005 protein_coding Mus_musculus 0 270
ENSMUST00000172895 Gm8810-001 unprocessed_pseudogene Mus_musculus 0 261
ENSMUST00000113760 H2-T24-001 protein_coding Mus_musculus 0 259
ENSMUST00000173127 Gm9574-001 unprocessed_pseudogene Mus_musculus 0 250
ENSMUST00000113667 H2-M5-004 protein_coding Mus_musculus 0 250
ENSMUST00000119193 H2-M6-ps-001 unprocessed_pseudogene Mus_musculus 0 239
ENSMUST00000073546 H2-M10.3-001 protein_coding Mus_musculus 0 235
ENSMUST00000023845 H2-M10.2-001 protein_coding Mus_musculus 0 233
ENSMUST00000174378 Gm4256-001 unprocessed_pseudogene Mus_musculus 0 228
ENSMUST00000169950 H2-M10.4-201 protein_coding Mus_musculus 0 224
ENSMUST00000057502 H2-M10.4-001 protein_coding Mus_musculus 0 224
ENSMUST00000041531 H2-M10.5-001 protein_coding Mus_musculus 0 219
ENSMUST00000173402 Gm5682-001 unprocessed_pseudogene Mus_musculus 0 217
ENSMUST00000041398 H2-M10.6-001 protein_coding Mus_musculus 0 213
ENSMUST00000174444 Gm4271-001 unprocessed_pseudogene Mus_musculus 0 195
ENSMUST00000041964 H2-M11-001 protein_coding Mus_musculus 8e-38 163

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