C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5'-3' exoribonuclease 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377191 XRN2-001 ENSG00000088930 9606 + 20:21303304-21389827 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377191
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377191 17.612±0.00 15.565±0.00 1.532±0.00 3.453±1.28 10.045±1.85 8.251±3.12 6.860±3.72 11.647±4.07 6.414±0.81 7.453±4.14 8.171±7.57 14.247±6.28 16.650±3.03 21.002±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097L CIL_00097L_0001 VISTA 20:20934152-21536594
CIL_0002ZA CIL_0002ZA_0001 CGP 20:21125983-21389827
CIL_0007P1 CIL_0007P1_0007 UCNEbase 20:21205523-21382653
CIL_0008VN CIL_0008VN_0001 VISTA 20:21207913-21809383
CIL_0003QC CIL_0003QC_0001 CGP 20:21303304-21398028

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000738 IDA DNA catabolic process, exonucleolytic
GO:0003676 IEA nucleic acid binding
GO:0004518 TAS nuclease activity
GO:0004527 IEA exonuclease activity
GO:0004534 TAS:IEA 5'-3' exoribonuclease activity
GO:0005515 IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005730 IDA nucleolus
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006353 IEA DNA-templated transcription, termination
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006396 TAS RNA processing
GO:0006397 IEA mRNA processing
GO:0006401 TAS RNA catabolic process
GO:0007283 IEP spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0008409 IDA 5'-3' exonuclease activity
GO:0016020 IDA membrane
GO:0016049 ISS cell growth
GO:0016070 ISS RNA metabolic process
GO:0016235 IDA aggresome
GO:0044822 IDA poly(A) RNA binding
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028921 Xrn2-001 protein_coding Mus_musculus 0 4418
ENSMUST00000147057 Xrn2-002 retained_intron Mus_musculus 0 649
ENSMUST00000137358 Xrn2-004 retained_intron Mus_musculus 0 292
ENSMUST00000136136 Xrn2-003 retained_intron Mus_musculus 0 252

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