C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polymerase (DNA directed), alpha 1, catalytic subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000379059 POLA1-001 ENSG00000101868 9606 + X:24693947-24996986 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverOvaryPlacentaTestisENST00000379059
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Ovary Placenta Testis
ENST00000379059 1.853±0.00 0.894±0.00 0.909±0.00 1.600±0.00 1.330±0.05 1.696±0.00 0.149±0.00 0.906±0.00 0.534±0.18 3.328±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084H CIL_00084H_0001 VISTA X:24441239-25041771
CIL_0008NE CIL_0008NE_0001 VISTA X:24504486-25106506
CIL_0008NF CIL_0008NF_0001 VISTA X:24546114-25147616
CIL_0008NL CIL_0008NL_0001 VISTA X:24576218-25177967
CIL_0008NM CIL_0008NM_0001 VISTA X:24597265-25200155
CIL_0008W8 CIL_0008W8_0001 VISTA X:24627531-25229450
CIL_0008W7 CIL_0008W7_0001 VISTA X:24689762-25291464
CIL_0001X9 CIL_0001X9_0002 CGP X:24693919-25015948

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000166 IDA:IEA nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0000785 IDA chromatin
GO:0001882 IEA nucleoside binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IDA:IEA DNA-directed DNA polymerase activity
GO:0003896 IDA DNA primase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005654 IDA nucleoplasm
GO:0005658 IDA alpha DNA polymerase:primase complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006260 IMP:IEA DNA replication
GO:0006269 IDA DNA replication, synthesis of RNA primer
GO:0006270 IDA DNA replication initiation
GO:0006271 IMP DNA strand elongation involved in DNA replication
GO:0006272 IDA leading strand elongation
GO:0006273 IDA lagging strand elongation
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0008283 IDA cell proliferation
GO:0008408 IBA 3'-5' exonuclease activity
GO:0016032 IEA viral process
GO:0016363 IDA nuclear matrix
GO:0019901 IPI protein kinase binding
GO:0019985 IBA translesion synthesis
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0090305 IBA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000006856 Pola1-001 protein_coding Mus_musculus 0 5428
ENSMUST00000142479 Pola1-004 processed_transcript Mus_musculus 0 484

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