C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin 2 receptor, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000379959 IL2RA-001 ENSG00000134460 9606 - 10:6010689-6062325 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartLiverMuscleOvaryPlacentaTestisENST00000379959
Transcript ID Adrenal Breast Colon Heart Liver Muscle Ovary Placenta Testis
ENST00000379959 4.209±0.00 0.258±0.02 0.318±0.00 0.120±0.00 0.103±0.00 0.019±0.00 0.350±0.19 0.968±0.44 0.065±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0004911 IEA interleukin-2 receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006915 TAS apoptotic process
GO:0006924 IEA activation-induced cell death of T cells
GO:0006955 TAS immune response
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007219 IEA Notch signaling pathway
GO:0008144 IEA drug binding
GO:0008283 TAS cell proliferation
GO:0009897 IEA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0019976 IEA interleukin-2 binding
GO:0038110 TAS interleukin-2-mediated signaling pathway
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042104 IEA positive regulation of activated T cell proliferation
GO:0042130 IEA negative regulation of T cell proliferation
GO:0043029 IEA T cell homeostasis
GO:0045582 IEA positive regulation of T cell differentiation
GO:0046013 IEA regulation of T cell homeostatic proliferation
GO:0050672 IEA negative regulation of lymphocyte proliferation
GO:0050687 IEA negative regulation of defense response to virus
GO:0050728 IEA negative regulation of inflammatory response
GO:0050777 IEA negative regulation of immune response

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167588 Trim67-201 protein_coding Mus_musculus 0.00000003 66
ENSMUST00000038562 Spsb1-001 protein_coding Mus_musculus 0.0002 53

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