C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382061 SERPINF2-001 ENSG00000167711 9606 + 17:1743026-1755268 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderHeartKidneyLiverOvaryPlacentaTestisENST00000382061
Transcript ID Bladder Heart Kidney Liver Ovary Placenta Testis
ENST00000382061 0.886±0.00 0.582±0.00 57.926±0.00 149.640±0.00 0.872±0.00 0.418±0.00 1.417±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060U CIL_00060U_0002 CGP 17:1742836-1777574

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0002034 ISS regulation of blood vessel size by renin-angiotensin
GO:0002576 TAS platelet degranulation
GO:0004866 TAS endopeptidase inhibitor activity
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005577 IDA fibrinogen complex
GO:0005615 IBA extracellular space
GO:0006953 IEA acute-phase response
GO:0007596 TAS blood coagulation
GO:0009986 IDA cell surface
GO:0010757 IDA negative regulation of plasminogen activation
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0030168 TAS platelet activation
GO:0030199 ISS collagen fibril organization
GO:0031093 TAS platelet alpha granule lumen
GO:0032967 IDA positive regulation of collagen biosynthetic process
GO:0042730 TAS fibrinolysis
GO:0042803 IPI protein homodimerization activity
GO:0045597 IDA positive regulation of cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IDA positive regulation of JNK cascade
GO:0048514 ISS blood vessel morphogenesis
GO:0048661 ISS positive regulation of smooth muscle cell proliferation
GO:0051496 IDA positive regulation of stress fiber assembly
GO:0051918 IDA negative regulation of fibrinolysis
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0071636 IDA positive regulation of transforming growth factor beta production
GO:0072562 IDA blood microparticle
GO:2000049 TAS positive regulation of cell-cell adhesion mediated by cadherin

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108437 Serpinf2-001 protein_coding Mus_musculus 0 1290
ENSMUST00000043696 Serpinf2-201 protein_coding Mus_musculus 0 1288
ENSMUST00000128330 Serpinf2-002 protein_coding Mus_musculus 0 691
ENSMUST00000142094 Serpinf2-003 nonsense_mediated_decay Mus_musculus 0 483

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