C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: doublesex and mab-3 related transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382276 DMRT1-001 ENSG00000137090 9606 + 9:841690-969090 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainTestisENST00000382276
Transcript ID Brain Testis
ENST00000382276 0.033±0.00 9.398±3.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YF CIL_0006YF_0002 CGP 9:470291-969090
CIL_0008UR CIL_0008UR_0001 VISTA 9:668797-1270093
CIL_0008NH CIL_0008NH_0001 VISTA 9:673435-1275288
CIL_0006Y7 CIL_0006Y7_0002 CGP 9:841690-991731

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IEA cell morphogenesis
GO:0000987 ISS core promoter proximal region sequence-specific DNA binding
GO:0002176 ISS male germ cell proliferation
GO:0003006 IEA developmental process involved in reproduction
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007283 IEA spermatogenesis
GO:0008354 IEA germ cell migration
GO:0008584 IEA male gonad development
GO:0030238 ISS male sex determination
GO:0035556 IEA intracellular signal transduction
GO:0042803 IEA protein homodimerization activity
GO:0043565 IEA sequence-specific DNA binding
GO:0045835 ISS negative regulation of meiosis
GO:0045840 ISS positive regulation of mitosis
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046661 ISS male sex differentiation
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048599 IEA oocyte development
GO:0060008 ISS Sertoli cell differentiation
GO:0060009 IEA Sertoli cell development
GO:0060903 IEA positive regulation of meiosis I
GO:1900107 IEA regulation of nodal signaling pathway
GO:2000020 IEA positive regulation of male gonad development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025755 Dmrt1-001 protein_coding Mus_musculus 0 1066
ENSMUST00000160814 Dmrt1-002 processed_transcript Mus_musculus 0 953
ENSMUST00000087525 Dmrt1-004 protein_coding Mus_musculus 0 490

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