C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class I, A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000383605 HLA-A-001 ENSG00000206505 9606 + CHR_HSCHR6_MHC_QBL_CTG1:29930625-29935265 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0005515 IEA protein binding
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 ISS cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0030881 ISS beta-2-microglobulin binding
GO:0031901 TAS early endosome membrane
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 ISS peptide antigen binding
GO:0042612 ISS:IEA MHC class I protein complex
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000172912 H2-K1-003 protein_coding Mus_musculus 0 817
ENSMUST00000025181 H2-K1-001 protein_coding Mus_musculus 0 798
ENSMUST00000114311 H2-K1-002 retained_intron Mus_musculus 0 784
ENSMUST00000097335 Gm8909-201 protein_coding Mus_musculus 0 773
ENSMUST00000040467 Gm8909-001 protein_coding Mus_musculus 0 773
ENSMUST00000173353 Gm8909-002 protein_coding Mus_musculus 0 773
ENSMUST00000174250 H2-K2-001 unprocessed_pseudogene Mus_musculus 0 743
ENSMUST00000074806 H2-Q2-001 protein_coding Mus_musculus 0 721
ENSMUST00000076256 H2-Q7-201 protein_coding Mus_musculus 0 712
ENSMUST00000078205 H2-Q7-202 protein_coding Mus_musculus 0 695
ENSMUST00000071951 H2-Q7-001 protein_coding Mus_musculus 0 695
ENSMUST00000172979 H2-Q5-001 polymorphic_pseudogene Mus_musculus 0 693
ENSMUST00000102678 H2-T23-001 protein_coding Mus_musculus 0 678
ENSMUST00000173075 H2-K1-010 protein_coding Mus_musculus 0 662
ENSMUST00000173080 H2-Bl-201 protein_coding Mus_musculus 0 656
ENSMUST00000172538 C920025E04Rik-001 unprocessed_pseudogene Mus_musculus 0 651
ENSMUST00000116598 H2-Q7-203 protein_coding Mus_musculus 0 448
ENSMUST00000173788 H2-Q7-003 retained_intron Mus_musculus 0 448
ENSMUST00000176712 H2-M5-002 protein_coding Mus_musculus 0 431
ENSMUST00000176784 H2-M5-005 protein_coding Mus_musculus 0 429
ENSMUST00000169189 H2-M5-001 protein_coding Mus_musculus 0 429
ENSMUST00000174854 H2-Q5-002 retained_intron Mus_musculus 0 424
ENSMUST00000145260 H2-M5-003 retained_intron Mus_musculus 0 414
ENSMUST00000174094 Gm10499-002 transcribed_unprocessed_pseudogene Mus_musculus 0 409
ENSMUST00000185087 H2-Bl-005 nonsense_mediated_decay Mus_musculus 0 403
ENSMUST00000184502 H2-Bl-008 protein_coding Mus_musculus 0 381
ENSMUST00000174839 H2-T23-002 retained_intron Mus_musculus 0 361
ENSMUST00000113667 H2-M5-004 protein_coding Mus_musculus 0 248
ENSMUST00000174471 H2-T23-005 retained_intron Mus_musculus 0 211
ENSMUST00000174161 H2-T23-003 retained_intron Mus_musculus 0 211
ENSMUST00000173402 Gm5682-001 unprocessed_pseudogene Mus_musculus 0 207
ENSMUST00000174778 Gm10499-001 retained_intron Mus_musculus 0 195
ENSMUST00000172782 H2-K1-007 processed_transcript Mus_musculus 1.99993e-41 174

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