C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: anaplastic lymphoma receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000389048 ALK-001 ENSG00000171094 9606 - 2:29192774-29921566 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonENST00000389048
Transcript ID Brain Breast Colon
ENST00000389048 0.464±0.00 0.037±0.00 0.097±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00013T CIL_00013T_0001 CGP 2:29097705-29921566
CIL_0000VI CIL_0000VI_0001 CGP 2:29192774-30160533

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0004672 IEA protein kinase activity
GO:0004704 TAS NF-kappaB-inducing kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 IEA nervous system development
GO:0008283 TAS cell proliferation
GO:0016020 IEA membrane
GO:0016310 TAS phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0038061 TAS NIK/NF-kappaB signaling
GO:0042981 TAS regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0046777 TAS protein autophosphorylation
GO:0048666 TAS neuron development
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000086639 Alk-201 protein_coding Mus_musculus 0 4806
ENSDART00000061547 ltk-002 protein_coding Danio_rerio 0 601
ENSDART00000062907 ltk-001 protein_coding Danio_rerio 0 601
ENSDART00000150116 alk-001 protein_coding Danio_rerio 0 556

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