C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: caspase recruitment domain family, member 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000391898 CARD8-202 ENSG00000105483 9606 - 19:48208104-48241063 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartKidneyLungOvaryPlacentaTestisENST00000391898
Transcript ID Adipose Breast Heart Kidney Lung Ovary Placenta Testis
ENST00000391898 2.279±0.00 2.132±0.00 1.580±0.00 1.585±0.24 1.868±0.00 1.095±0.00 1.744±0.21 1.980±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008656 IDA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0032089 IPI NACHT domain binding
GO:0042803 IDA protein homodimerization activity
GO:0042981 IEA regulation of apoptotic process
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050718 IDA positive regulation of interleukin-1 beta secretion
GO:0072559 IDA NLRP3 inflammasome complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168162 Pdgfra-202 protein_coding Mus_musculus 0.0001 55
ENSMUST00000000476 Pdgfra-201 protein_coding Mus_musculus 0.0001 55

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