C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392132 XRCC5-201 ENSG00000079246 9606 + 2:216109297-216206291 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392132
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392132 60.228±0.00 58.191±0.00 7.387±0.00 34.204±16.28 25.731±11.53 31.561±18.14 16.554±12.65 29.841±15.03 16.560±1.29 27.648±19.13 24.299±17.41 44.740±16.85 49.814±11.03 63.418±7.68

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ME CIL_0005ME_0001 CGP 2:216081866-216206303
CIL_0000AO CIL_0000AO_0002 CGP 2:216107464-216372027

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000723 IEA:TAS telomere maintenance
GO:0000783 TAS nuclear telomere cap complex
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0003677 NAS:IEA DNA binding
GO:0003684 IEA damaged DNA binding
GO:0003690 TAS double-stranded DNA binding
GO:0003691 IDA double-stranded telomeric DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006281 TAS DNA repair
GO:0006302 TAS double-strand break repair
GO:0006303 IEA:TAS double-strand break repair via nonhomologous end joining
GO:0006310 IEA DNA recombination
GO:0006351 IEA transcription, DNA-templated
GO:0008022 IPI protein C-terminus binding
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016817 IEA hydrolase activity, acting on acid anhydrides
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032481 TAS positive regulation of type I interferon production
GO:0032508 IEA DNA duplex unwinding
GO:0042162 IEA:IDA telomeric DNA binding
GO:0043564 IEA:IDA Ku70:Ku80 complex
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0051575 IMP 5'-deoxyribose-5-phosphate lyase activity
GO:0070419 IDA nonhomologous end joining complex
GO:0075713 TAS establishment of integrated proviral latency

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027379 Xrcc5-201 protein_coding Mus_musculus 0 2191

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