C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NCK adaptor protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000393349 NCK2-002 ENSG00000071051 9606 + 2:105851782-105894272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000393349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000393349 6.624±0.00 10.979±0.00 0.588±0.00 3.624±0.78 7.350±0.00 11.367±0.00 0.315±0.00 1.035±0.00 9.495±0.00 12.586±0.00 6.170±0.00 6.751±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00010G CIL_00010G_0001 CGP 2:105357712-105894274
CIL_0003Y7 CIL_0003Y7_0001 CGP 2:105744897-106078159

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005737 NAS cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0006417 IEA regulation of translation
GO:0007165 TAS signal transduction
GO:0007172 NAS signal complex assembly
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007176 TAS regulation of epidermal growth factor-activated receptor activity
GO:0007411 TAS axon guidance
GO:0008093 NAS cytoskeletal adaptor activity
GO:0008285 TAS negative regulation of cell proliferation
GO:0030159 NAS receptor signaling complex scaffold activity
GO:0030838 IMP positive regulation of actin filament polymerization
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042110 NAS T cell activation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000086421 Nck2-001 protein_coding Mus_musculus 0 1424
ENSMUST00000117765 Gm6226-001 processed_pseudogene Mus_musculus 0 1260
ENSDART00000132648 nck1b-001 protein_coding Danio_rerio 0 379
ENSDART00000109339 nck1b-201 protein_coding Danio_rerio 0 374
ENSMUST00000114744 Nck2-005 protein_coding Mus_musculus 0 311
ENSDART00000134577 nck1b-002 processed_transcript Danio_rerio 4.2039e-45 187
ENSMUST00000187435 Nck2-007 protein_coding Mus_musculus 2e-28 132

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