C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neurotrophic tyrosine kinase, receptor, type 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394480 NTRK3-001 ENSG00000140538 9606 - 15:87859751-88256747 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000394480
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000394480 0.397±0.00 1.410±0.00 0.406±0.00 0.135±0.00 0.171±0.00 0.138±0.12 0.010±0.00 0.131±0.01 0.003±0.00 0.024±0.00 0.127±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NY CIL_0000NY_0001 CGP 15:86141996-88256768
CIL_0001AZ CIL_0001AZ_0001 CGP 15:87859751-88467419

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0002039 IPI p53 binding
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005030 IDA neurotrophin receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0010628 IDA positive regulation of gene expression
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030335 IDA positive regulation of cell migration
GO:0032148 IDA activation of protein kinase B activity
GO:0032856 IDA activation of Ras GTPase activity
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0038179 IEA neurotrophin signaling pathway
GO:0043121 TAS neurotrophin binding
GO:0043235 IDA receptor complex
GO:0050927 IDA positive regulation of positive chemotaxis
GO:2000251 IDA positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000039431 Ntrk3-001 protein_coding Mus_musculus 0 3539
ENSMUST00000039438 Ntrk3-002 protein_coding Mus_musculus 0 2169
ENSMUST00000155795 Ntrk3-003 retained_intron Mus_musculus 0 1932
ENSDART00000091727 ntrk3a-201 protein_coding Danio_rerio 0 909
ENSDART00000002966 ntrk2b-201 protein_coding Danio_rerio 0 473
ENSDART00000135885 ntrk2b-001 protein_coding Danio_rerio 0 446
ENSMUST00000029712 Ntrk1-201 protein_coding Mus_musculus 0 346
ENSMUST00000151885 Ntrk3-004 processed_transcript Mus_musculus 0 243

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