C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: interleukin 4 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395762 IL4R-001 ENSG00000077238 9606 + 16:27313913-27364778 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaENST00000395762
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta
ENST00000395762 8.102±0.00 9.960±0.00 3.538±0.00 1.823±0.68 3.152±1.50 1.636±0.00 3.735±0.71 3.083±1.58 0.144±0.00 7.635±3.78 6.800±1.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005KN CIL_0005KN_0001 CGP 16:27224991-27364778
CIL_0005KO CIL_0005KO_0001 CGP 16:27313668-27452042

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002532 IEA production of molecular mediator involved in inflammatory response
GO:0004896 IEA cytokine receptor activity
GO:0004913 TAS interleukin-4 receptor activity
GO:0005057 TAS receptor signaling protein activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IEA extracellular space
GO:0005887 TAS integral component of plasma membrane
GO:0006955 TAS immune response
GO:0007165 TAS signal transduction
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030728 IEA ovulation
GO:0035556 TAS intracellular signal transduction
GO:0035771 TAS interleukin-4-mediated signaling pathway
GO:0042127 IEA regulation of cell proliferation
GO:0042832 IEA defense response to protozoan
GO:0043032 IEA positive regulation of macrophage activation
GO:0043235 IDA receptor complex
GO:0043627 IEA response to estrogen
GO:0045626 IEA negative regulation of T-helper 1 cell differentiation
GO:0045630 IEA positive regulation of T-helper 2 cell differentiation
GO:0090197 IEA positive regulation of chemokine secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000159255 Mettl13-002 retained_intron Mus_musculus 0.00007 55

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