C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon induced transmembrane protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000399817 IFITM2-001 ENSG00000185201 9606 + 11:308163-309395 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000399817
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000399817 125.430±0.00 228.629±0.00 10.554±8.10 67.631±0.00 154.781±0.00 34.251±31.68 137.623±0.00 165.550±0.00 241.720±238.53 53.054±0.00 116.365±78.21 108.215±65.20 47.653±40.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UF CIL_0002UF_0001 CGP 11:298200-315272
CIL_0002UG CIL_0002UG_0001 CGP 11:307631-315272

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005886 TAS plasma membrane
GO:0006955 TAS immune response
GO:0009607 IEA response to biotic stimulus
GO:0009615 IDA response to virus
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0034341 IDA response to interferon-gamma
GO:0035455 IDA response to interferon-alpha
GO:0035456 IDA response to interferon-beta
GO:0045071 IDA negative regulation of viral genome replication
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000116005 Gm11951-001 processed_pseudogene Mus_musculus 0 224
ENSMUST00000081649 Ifitm2-201 protein_coding Mus_musculus 0 213
ENSMUST00000026564 Ifitm1-003 protein_coding Mus_musculus 0 211
ENSMUST00000106040 Ifitm1-002 protein_coding Mus_musculus 0 211
ENSMUST00000106042 Ifitm1-001 protein_coding Mus_musculus 0 211
ENSMUST00000026565 Ifitm3-001 protein_coding Mus_musculus 0 211
ENSMUST00000176080 Taf6l-006 retained_intron Mus_musculus 1e-25 121

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