C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MAP/microtubule affinity-regulating kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000402010 MARK2-202 ENSG00000072518 9606 + 11:63838928-63911019 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonLungOvaryPlacentaENST00000402010
Transcript ID Adipose Brain Breast Colon Lung Ovary Placenta
ENST00000402010 1.463±0.00 1.610±0.00 2.249±0.00 1.110±0.00 2.330±0.00 5.081±0.23 2.492±1.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004M6 CIL_0004M6_0002 CGP 11:63838928-63916844

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0000422 NAS mitochondrion degradation
GO:0001764 ISS neuron migration
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 IEA nucleus
GO:0005739 NAS mitochondrion
GO:0005884 IDA actin filament
GO:0005886 IDA plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0008289 IEA lipid binding
GO:0010976 IDA positive regulation of neuron projection development
GO:0016020 IMP membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016328 IDA lateral plasma membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018107 TAS peptidyl-threonine phosphorylation
GO:0030010 IDA establishment of cell polarity
GO:0030295 TAS protein kinase activator activity
GO:0032147 TAS activation of protein kinase activity
GO:0035556 IDA intracellular signal transduction
GO:0044822 IDA poly(A) RNA binding
GO:0045180 IEA basal cortex
GO:0045197 IDA establishment or maintenance of epithelial cell apical/basal polarity
GO:0046777 ISS protein autophosphorylation
GO:0050321 ISS tau-protein kinase activity
GO:0050770 IMP regulation of axonogenesis
GO:0051493 ISS regulation of cytoskeleton organization
GO:0051646 NAS mitochondrion localization
GO:0097427 IDA microtubule bundle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165965 Mark2-005 protein_coding Mus_musculus 0 3860
ENSMUST00000171721 Mark2-007 protein_coding Mus_musculus 0 3685
ENSMUST00000051711 Mark2-201 protein_coding Mus_musculus 0 3653
ENSMUST00000025921 Mark2-006 protein_coding Mus_musculus 0 3459
ENSMUST00000165286 Mark2-002 protein_coding Mus_musculus 0 2924
ENSMUST00000032557 Mark2-001 protein_coding Mus_musculus 0 2924
ENSMUST00000164205 Mark2-003 protein_coding Mus_musculus 0 2918
ENSMUST00000168872 Mark2-008 protein_coding Mus_musculus 0 2135
ENSMUST00000165881 Mark2-016 protein_coding Mus_musculus 0 1062
ENSMUST00000171393 Mark2-011 protein_coding Mus_musculus 0 944
ENSMUST00000166461 Mark2-019 protein_coding Mus_musculus 0 900
ENSMUST00000168852 Mark2-014 retained_intron Mus_musculus 0 839
ENSMUST00000164129 Mark2-018 nonsense_mediated_decay Mus_musculus 0 830
ENSMUST00000169541 Mark2-013 protein_coding Mus_musculus 0 780
ENSMUST00000171044 Mark2-021 retained_intron Mus_musculus 0 728
ENSMUST00000163345 Mark2-020 protein_coding Mus_musculus 0 656
ENSMUST00000167767 Mark2-017 protein_coding Mus_musculus 0 466
ENSMUST00000165989 Mark2-010 protein_coding Mus_musculus 0 460
ENSMUST00000171352 Mark2-009 protein_coding Mus_musculus 0 435
ENSMUST00000170768 Mark2-015 retained_intron Mus_musculus 0 407
ENSMUST00000168324 Mark2-012 protein_coding Mus_musculus 0 250
ENSMUST00000075281 Mark3-201 protein_coding Mus_musculus 0 213
ENSMUST00000084953 Mark3-202 protein_coding Mus_musculus 0 213
ENSDART00000041293 mark3-201 protein_coding Danio_rerio 4e-28 132
ENSDART00000013525 mark3-001 protein_coding Danio_rerio 4e-28 132
ENSDART00000133342 mark3-007 protein_coding Danio_rerio 4e-28 132
ENSDART00000134972 mark3-006 protein_coding Danio_rerio 4e-28 132
ENSDART00000138991 mark3-005 protein_coding Danio_rerio 4e-28 132
ENSDART00000134240 mark3-004 protein_coding Danio_rerio 4e-28 132
ENSDART00000005329 mark2b-201 protein_coding Danio_rerio 7e-16 92

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