C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: autophagy related 4B, cysteine peptidase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000404914 ATG4B-002 ENSG00000168397 9606 + 2:241637612-241673857 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000404914
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000404914 5.561±0.00 1.140±0.00 6.460±3.53 3.419±2.15 5.735±0.00 2.570±1.94 9.526±0.00 2.515±0.48 2.912±0.95 10.087±5.98 11.383±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004U9 CIL_0004U9_0002 CGP 2:241558721-241637449
CIL_0003ST CIL_0003ST_0001 CGP 2:241584405-241673857
CIL_0004UA CIL_0004UA_0002 CGP 2:241637213-241686991

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000045 IGI autophagic vacuole assembly
GO:0004175 IDA endopeptidase activity
GO:0005515 IPI protein binding
GO:0005737 IEA:ISS cytoplasm
GO:0006508 IEA:IDA proteolysis
GO:0006914 IEA:IGI autophagy
GO:0008233 IEA peptidase activity
GO:0008234 IEA:IDA cysteine-type peptidase activity
GO:0010508 IDA positive regulation of autophagy
GO:0015031 IEA protein transport
GO:0045732 IEA positive regulation of protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027502 Atg4b-001 protein_coding Mus_musculus 0 1480
ENSMUST00000135762 Atg4b-002 retained_intron Mus_musculus 0 808
ENSMUST00000149436 Atg4b-003 protein_coding Mus_musculus 0 566
ENSMUST00000185754 Atg4b-008 retained_intron Mus_musculus 0 233
ENSMUST00000186811 Atg4b-011 nonsense_mediated_decay Mus_musculus 0 233
ENSMUST00000187824 Atg4b-005 protein_coding Mus_musculus 0 231
ENSMUST00000186124 Atg4b-009 retained_intron Mus_musculus 2e-38 165

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