C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 1, group H, member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000411902 NR1H2-003 ENSG00000131408 9606 + 19:50376459-50382731 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartOvaryTestisENST00000411902
Transcript ID Adipose Adrenal Breast Heart Ovary Testis
ENST00000411902 14.772±0.00 12.566±0.00 8.900±0.00 0.624±0.00 4.281±0.00 10.733±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IL CIL_0004IL_0001 CGP 19:50329653-50382982

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 TAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0010745 IC negative regulation of macrophage derived foam cell differentiation
GO:0010867 IMP positive regulation of triglyceride biosynthetic process
GO:0010875 IMP positive regulation of cholesterol efflux
GO:0010887 IMP negative regulation of cholesterol storage
GO:0032270 IMP positive regulation of cellular protein metabolic process
GO:0032369 IMP negative regulation of lipid transport
GO:0032376 IDA positive regulation of cholesterol transport
GO:0034191 IPI apolipoprotein A-I receptor binding
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0045723 IMP positive regulation of fatty acid biosynthetic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048550 IMP negative regulation of pinocytosis
GO:0051006 IMP positive regulation of lipoprotein lipase activity
GO:0051117 IPI ATPase binding
GO:0060336 NAS negative regulation of interferon-gamma-mediated signaling pathway
GO:2000188 ISS regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167197 Nr1h2-201 protein_coding Mus_musculus 0 1011
ENSMUST00000107910 Nr1h2-003 protein_coding Mus_musculus 0 1011
ENSMUST00000107911 Nr1h2-002 protein_coding Mus_musculus 0 1011
ENSMUST00000073488 Nr1h2-001 protein_coding Mus_musculus 0 1011
ENSMUST00000107912 Nr1h2-004 protein_coding Mus_musculus 0 1011
ENSMUST00000123358 Nr1h2-006 retained_intron Mus_musculus 0 806
ENSMUST00000128354 Nr1h2-012 retained_intron Mus_musculus 0 433
ENSMUST00000137674 Nr1h2-011 retained_intron Mus_musculus 0 407
ENSMUST00000111354 Nr1h3-002 protein_coding Mus_musculus 0 366
ENSMUST00000002177 Nr1h3-001 protein_coding Mus_musculus 0 366
ENSMUST00000111356 Nr1h3-007 protein_coding Mus_musculus 0 366
ENSMUST00000132769 Nr1h2-005 retained_intron Mus_musculus 0 241
ENSMUST00000130031 Nr1h3-005 retained_intron Mus_musculus 0 226
ENSMUST00000111355 Nr1h3-003 protein_coding Mus_musculus 0 226
ENSMUST00000150654 Nr1h3-004 retained_intron Mus_musculus 0 226

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