C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine/threonine kinase receptor associated protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419869 STRAP-001 ENSG00000023734 9606 + 12:15882395-15903478 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000419869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000419869 45.547±0.00 21.894±0.00 6.060±0.00 27.920±8.17 28.076±15.03 22.394±12.35 22.492±15.05 26.674±16.31 14.683±5.22 21.682±15.69 19.190±9.31 38.843±7.87 33.875±3.16 27.113±8.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007F9 CIL_0007F9_0001 CGP 12:15620158-15903478
CIL_000896 CIL_000896_0001 VISTA 12:15717656-16318890
CIL_0005FF CIL_0005FF_0001 CGP 12:15882391-16037282

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000387 IDA spliceosomal snRNP assembly
GO:0005102 IEA receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0030054 IDA cell junction
GO:0030277 IMP maintenance of gastrointestinal epithelium
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032797 IDA SMN complex
GO:0034719 IDA SMN-Sm protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0060394 IMP negative regulation of pathway-restricted SMAD protein phosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064910 Strap-001 protein_coding Mus_musculus 0 1615
ENSMUST00000122047 Gm12570-001 processed_pseudogene Mus_musculus 0 809
ENSMUST00000137235 Strap-003 processed_transcript Mus_musculus 2e-32 145

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