Transcript Info |
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Description: | neurofibromin 2 (merlin) | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000432151 | NF2-002 | ENSG00000186575 | 9606 | + | 22:29603949-29694945 | nonsense_mediated_decay |
Expression PatternsNo expression data. |
Conserved Regions |
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Gene is not located within a conserved region. |
Gene Ontology | ||
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GO ID | Evidence Type | GO Description |
GO:0001953 | TAS | negative regulation of cell-matrix adhesion |
GO:0003779 | IEA | actin binding |
GO:0005515 | IPI | protein binding |
GO:0005634 | IDA | nucleus |
GO:0005730 | IDA | nucleolus |
GO:0005737 | IDA | cytoplasm |
GO:0005769 | IDA | early endosome |
GO:0005856 | TAS:IEA | cytoskeleton |
GO:0005886 | IDA | plasma membrane |
GO:0008156 | IMP | negative regulation of DNA replication |
GO:0008285 | IDA | negative regulation of cell proliferation |
GO:0014010 | IMP | Schwann cell proliferation |
GO:0016020 | IDA | membrane |
GO:0019898 | IEA | extrinsic component of membrane |
GO:0022408 | IDA | negative regulation of cell-cell adhesion |
GO:0030036 | IMP | actin cytoskeleton organization |
GO:0030336 | TAS | negative regulation of cell migration |
GO:0035330 | IMP | regulation of hippo signaling |
GO:0042518 | IDA | negative regulation of tyrosine phosphorylation of Stat3 protein |
GO:0042524 | IDA | negative regulation of tyrosine phosphorylation of Stat5 protein |
GO:0046426 | IDA | negative regulation of JAK-STAT cascade |
GO:0048471 | IDA | perinuclear region of cytoplasm |
GO:0051496 | IMP | positive regulation of stress fiber assembly |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000152656 | Nf2-008 | nonsense_mediated_decay | Mus_musculus | 0 | 837 |
ENSMUST00000109908 | Nf2-003 | processed_transcript | Mus_musculus | 0 | 496 |
ENSMUST00000093374 | Nf2-013 | protein_coding | Mus_musculus | 0 | 496 |
ENSMUST00000053079 | Nf2-004 | protein_coding | Mus_musculus | 0 | 496 |
ENSMUST00000056290 | Nf2-002 | protein_coding | Mus_musculus | 0 | 496 |
ENSMUST00000109910 | Nf2-001 | protein_coding | Mus_musculus | 0 | 496 |
ENSMUST00000155600 | Nf2-006 | processed_transcript | Mus_musculus | 0 | 466 |
ENSMUST00000164190 | Nf2-007 | protein_coding | Mus_musculus | 0 | 296 |
ENSMUST00000137926 | Nf2-012 | protein_coding | Mus_musculus | 0 | 196 |
ENSMUST00000172305 | Nf2-010 | protein_coding | Mus_musculus | 2.99878e-43 | 180 |
ENSMUST00000141342 | Nf2-009 | retained_intron | Mus_musculus | 5e-21 | 106 |