C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family A (ABC1), member 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000435683 ABCA7-002 ENSG00000064687 9606 + 19:1042625-1065572 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastKidneyLiverLungPlacentaTestisENST00000435683
Transcript ID Adipose Brain Breast Kidney Liver Lung Placenta Testis
ENST00000435683 0.660±0.00 0.110±0.00 0.272±0.00 0.764±0.00 0.312±0.00 1.524±0.00 1.687±0.00 0.619±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0000I2 CIL_0000I2_0001 CGP 19:1026581-1065572
CIL_0000HU CIL_0000HU_0001 CGP 19:1040101-1086628

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001891 ISS phagocytic cup
GO:0005215 TAS transporter activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006909 IEA phagocytosis
GO:0007613 ISS memory
GO:0009986 ISS cell surface
GO:0010875 ISS positive regulation of cholesterol efflux
GO:0016021 TAS integral component of membrane
GO:0016887 IDA:IEA ATPase activity
GO:0017121 IDA phospholipid scrambling
GO:0018149 ISS peptide cross-linking
GO:0032587 ISS ruffle membrane
GO:0032780 IDA negative regulation of ATPase activity
GO:0032781 IDA positive regulation of ATPase activity
GO:0033344 IDA cholesterol efflux
GO:0033700 IDA phospholipid efflux
GO:0034188 IDA apolipoprotein A-I receptor activity
GO:0034380 IDA high-density lipoprotein particle assembly
GO:0034504 ISS protein localization to nucleus
GO:0038027 IDA apolipoprotein A-I-mediated signaling pathway
GO:0042985 ISS negative regulation of amyloid precursor protein biosynthetic process
GO:0043190 TAS ATP-binding cassette (ABC) transporter complex
GO:0050766 ISS positive regulation of phagocytosis
GO:0055085 TAS transmembrane transport
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:1900223 ISS positive regulation of beta-amyloid clearance
GO:1901076 ISS positive regulation of engulfment of apoptotic cell
GO:1902430 ISS negative regulation of beta-amyloid formation
GO:1902995 ISS positive regulation of phospholipid efflux

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000171637 Abca7-202 protein_coding Mus_musculus 0 1984
ENSMUST00000043866 Abca7-201 protein_coding Mus_musculus 0 1984
ENSMUST00000132517 Abca7-001 protein_coding Mus_musculus 0 1984

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