C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000440480 CDKN1C-003 ENSG00000129757 9606 - 11:2883218-2885813 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000440480
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000440480 51.502±0.00 3.334±0.00 1.474±0.00 11.454±6.42 13.734±11.44 7.980±7.06 11.161±9.22 52.020±51.45 3.938±1.39 12.040±7.90 9.337±6.91 21.510±9.55 398.176±93.69 4.128±2.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A3 CIL_0008A3_0001 VISTA 11:2289701-2893486
CIL_0003FM CIL_0003FM_0002 CGP 11:2444684-2885881

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004861 IEA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005737 IDA cytoplasm
GO:0007050 IEA cell cycle arrest
GO:0030511 IMP positive regulation of transforming growth factor beta receptor signaling pathway
GO:0033673 IDA negative regulation of kinase activity
GO:0042326 IDA negative regulation of phosphorylation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000037287 Cdkn1c-201 protein_coding Mus_musculus 0 484
ENSMUST00000167912 Cdkn1c-202 protein_coding Mus_musculus 0 357

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