C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: profilin 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000452853 PFN2-002 ENSG00000070087 9606 - 3:149964904-149970950 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLungOvaryPlacentaTestisENST00000452853
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Lung Ovary Placenta Testis
ENST00000452853 21.192±0.00 5.095±0.00 4.608±0.00 50.143±0.00 19.458±0.00 15.769±0.00 30.098±0.00 11.827±0.00 18.626±7.57 7.727±2.04 24.536±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002R7 CIL_0002R7_0001 CGP 3:149738470-149968385
CIL_0002R6 CIL_0002R6_0001 CGP 3:149761105-149968385
CIL_0002R5 CIL_0002R5_0001 CGP 3:149812708-150050788
CIL_0002QZ CIL_0002QZ_0001 CGP 3:149964904-150466431

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000774 IDA adenyl-nucleotide exchange factor activity
GO:0003779 IEA actin binding
GO:0003785 IPI actin monomer binding
GO:0005515 IPI protein binding
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0030036 IEA actin cytoskeleton organization
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0030838 IGI positive regulation of actin filament polymerization
GO:0032233 IMP positive regulation of actin filament bundle assembly
GO:0032781 IDA positive regulation of ATPase activity
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0070062 IDA extracellular vesicular exosome
GO:1900028 IMP negative regulation of ruffle assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066882 Pfn2-001 protein_coding Mus_musculus 0 1133
ENSMUST00000119344 Pfn2-002 protein_coding Mus_musculus 0 1127
ENSMUST00000120289 Pfn2-003 protein_coding Mus_musculus 0 525
ENSMUST00000122210 Pfn2-004 protein_coding Mus_musculus 0 311

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