C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: major histocompatibility complex, class I, A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000454091 HLA-A-001 ENSG00000223980 9606 + CHR_HSCHR6_MHC_SSTO_CTG1:29930538-29935179 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0005515 IEA protein binding
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 ISS cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0030881 ISS beta-2-microglobulin binding
GO:0031901 TAS early endosome membrane
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 ISS peptide antigen binding
GO:0042612 ISS:IEA MHC class I protein complex
GO:0046977 IDA TAP binding
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000172785 H2-D1-001 protein_coding Mus_musculus 0 832
ENSMUST00000172912 H2-K1-003 protein_coding Mus_musculus 0 822
ENSMUST00000025181 H2-K1-001 protein_coding Mus_musculus 0 804
ENSMUST00000114311 H2-K1-002 retained_intron Mus_musculus 0 789
ENSMUST00000097335 Gm8909-201 protein_coding Mus_musculus 0 761
ENSMUST00000040467 Gm8909-001 protein_coding Mus_musculus 0 761
ENSMUST00000173353 Gm8909-002 protein_coding Mus_musculus 0 761
ENSMUST00000068291 H2-Q10-201 protein_coding Mus_musculus 0 752
ENSMUST00000174525 H2-Q10-001 protein_coding Mus_musculus 0 752
ENSMUST00000076256 H2-Q7-201 protein_coding Mus_musculus 0 730
ENSMUST00000078205 H2-Q7-202 protein_coding Mus_musculus 0 723
ENSMUST00000071951 H2-Q7-001 protein_coding Mus_musculus 0 723
ENSMUST00000081435 H2-Q4-001 protein_coding Mus_musculus 0 717
ENSMUST00000172979 H2-Q5-001 polymorphic_pseudogene Mus_musculus 0 704
ENSMUST00000113879 H2-Q6-201 protein_coding Mus_musculus 0 702
ENSMUST00000174699 H2-Q6-001 protein_coding Mus_musculus 0 702
ENSMUST00000074806 H2-Q2-001 protein_coding Mus_musculus 0 699
ENSMUST00000174250 H2-K2-001 unprocessed_pseudogene Mus_musculus 0 693
ENSMUST00000173075 H2-K1-010 protein_coding Mus_musculus 0 678
ENSMUST00000073208 H2-Q1-001 protein_coding Mus_musculus 0 662
ENSMUST00000105041 H2-Q1-002 protein_coding Mus_musculus 0 654
ENSMUST00000102678 H2-T23-001 protein_coding Mus_musculus 0 628
ENSMUST00000173080 H2-Bl-201 protein_coding Mus_musculus 0 623
ENSMUST00000172538 C920025E04Rik-001 unprocessed_pseudogene Mus_musculus 0 595
ENSMUST00000173625 Gm8909-004 processed_transcript Mus_musculus 0 525
ENSMUST00000173975 H2-Q4-002 retained_intron Mus_musculus 0 514
ENSMUST00000113742 Gm11127-001 protein_coding Mus_musculus 0 472
ENSMUST00000174778 Gm10499-001 retained_intron Mus_musculus 0 470
ENSMUST00000116598 H2-Q7-203 protein_coding Mus_musculus 0 464
ENSMUST00000173788 H2-Q7-003 retained_intron Mus_musculus 0 464
ENSMUST00000172994 H2-Q1-003 retained_intron Mus_musculus 0 446
ENSMUST00000046131 Gm7030-201 protein_coding Mus_musculus 0 440
ENSMUST00000173322 Gm7030-001 protein_coding Mus_musculus 0 440
ENSMUST00000172968 Gm7030-202 protein_coding Mus_musculus 0 431
ENSMUST00000174854 H2-Q5-002 retained_intron Mus_musculus 0 424
ENSMUST00000174094 Gm10499-002 transcribed_unprocessed_pseudogene Mus_musculus 0 414
ENSMUST00000185087 H2-Bl-005 nonsense_mediated_decay Mus_musculus 0 390
ENSMUST00000184502 H2-Bl-008 protein_coding Mus_musculus 0 353
ENSMUST00000173133 H2-T3-006 nonsense_mediated_decay Mus_musculus 0 339
ENSMUST00000102675 H2-T3-001 protein_coding Mus_musculus 0 339
ENSMUST00000171139 H2-M2-002 protein_coding Mus_musculus 0 329
ENSMUST00000016427 H2-M2-001 protein_coding Mus_musculus 0 329
ENSMUST00000173435 H2-T3-007 retained_intron Mus_musculus 0 326
ENSMUST00000174839 H2-T23-002 retained_intron Mus_musculus 0 322
ENSMUST00000173577 H2-T3-004 retained_intron Mus_musculus 0 318
ENSMUST00000087189 H2-K1-005 protein_coding Mus_musculus 0 316
ENSMUST00000174161 H2-T23-003 retained_intron Mus_musculus 0 313
ENSMUST00000038580 H2-M3-001 protein_coding Mus_musculus 0 313
ENSMUST00000174693 Gm8909-003 processed_transcript Mus_musculus 0 303
ENSMUST00000077960 H2-T22-002 protein_coding Mus_musculus 0 300
ENSMUST00000080015 H2-T22-001 protein_coding Mus_musculus 0 300
ENSMUST00000173280 H2-T22-005 nonsense_mediated_decay Mus_musculus 0 300
ENSMUST00000173317 H2-K1-009 retained_intron Mus_musculus 0 300
ENSMUST00000173602 H2-K1-004 retained_intron Mus_musculus 0 300
ENSMUST00000166442 H2-T10-201 protein_coding Mus_musculus 0 300
ENSMUST00000174382 H2-T10-003 polymorphic_pseudogene Mus_musculus 0 300
ENSMUST00000174625 H2-T10-004 retained_intron Mus_musculus 0 300
ENSMUST00000174325 H2-D1-005 retained_intron Mus_musculus 0 294
ENSMUST00000058801 H2-T22-003 protein_coding Mus_musculus 0 292
ENSMUST00000172633 H2-T22-004 retained_intron Mus_musculus 0 292
ENSMUST00000174589 H2-Q10-002 retained_intron Mus_musculus 0 287
ENSMUST00000185167 H2-Bl-002 nonsense_mediated_decay Mus_musculus 0 287
ENSMUST00000184850 H2-Bl-006 retained_intron Mus_musculus 0 287
ENSMUST00000173016 H2-Q7-002 retained_intron Mus_musculus 0 281
ENSMUST00000025312 H2-T3-005 protein_coding Mus_musculus 0 274
ENSMUST00000095300 H2-T3-003 nonsense_mediated_decay Mus_musculus 0 267
ENSMUST00000174101 H2-T3-002 nonsense_mediated_decay Mus_musculus 0 267
ENSMUST00000172663 H2-T3-008 nonsense_mediated_decay Mus_musculus 0 267
ENSMUST00000173629 H2-T3-009 nonsense_mediated_decay Mus_musculus 0 267
ENSMUST00000173127 Gm9574-001 unprocessed_pseudogene Mus_musculus 0 254
ENSMUST00000172895 Gm8810-001 unprocessed_pseudogene Mus_musculus 0 248
ENSMUST00000073546 H2-M10.3-001 protein_coding Mus_musculus 0 222
ENSMUST00000174378 Gm4256-001 unprocessed_pseudogene Mus_musculus 0 219
ENSMUST00000023845 H2-M10.2-001 protein_coding Mus_musculus 0 217
ENSMUST00000173402 Gm5682-001 unprocessed_pseudogene Mus_musculus 0 207
ENSMUST00000041531 H2-M10.5-001 protein_coding Mus_musculus 0 207
ENSMUST00000169950 H2-M10.4-201 protein_coding Mus_musculus 0 206
ENSMUST00000057502 H2-M10.4-001 protein_coding Mus_musculus 0 206
ENSMUST00000041398 H2-M10.6-001 protein_coding Mus_musculus 0 202
ENSMUST00000174471 H2-T23-005 retained_intron Mus_musculus 0 198
ENSMUST00000172782 H2-K1-007 processed_transcript Mus_musculus 0 191
ENSMUST00000174444 Gm4271-001 unprocessed_pseudogene Mus_musculus 4.06377e-44 183
ENSMUST00000041964 H2-M11-001 protein_coding Mus_musculus 2e-36 158

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