C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000474194 RFWD2-006 ENSG00000143207 9606 - 1:176135010-176207083 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLiverMuscleENST00000474194
Transcript ID Breast Heart Liver Muscle
ENST00000474194 4.232±0.00 0.805±0.00 3.028±0.00 0.995±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008270 IEA zinc ion binding
GO:0010212 IDA response to ionizing radiation
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0061630 IMP ubiquitin protein ligase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000076894 Rfwd2-201 protein_coding Mus_musculus 0 647
ENSMUST00000133472 Gm6206-001 processed_pseudogene Mus_musculus 0 593
ENSMUST00000190923 RP23-133G16.5-001 processed_pseudogene Mus_musculus 0 252
ENSMUST00000190342 RP23-293C19.3-001 processed_pseudogene Mus_musculus 0 241
ENSMUST00000120979 Gm15861-001 processed_pseudogene Mus_musculus 0 239
ENSMUST00000117327 Gm14670-001 processed_pseudogene Mus_musculus 0 228
ENSMUST00000191422 RP24-286I24.2-001 processed_pseudogene Mus_musculus 0 220
ENSMUST00000121678 Gm13356-001 processed_pseudogene Mus_musculus 0 200
ENSMUST00000117170 Gm14894-001 processed_pseudogene Mus_musculus 2e-39 167
ENSMUST00000121711 Gm13419-001 processed_pseudogene Mus_musculus 1e-37 161
ENSMUST00000121699 Gm15065-001 processed_pseudogene Mus_musculus 1e-37 161
ENSMUST00000121483 Gm13210-001 processed_pseudogene Mus_musculus 1e-36 158
ENSMUST00000120617 Gm13396-001 processed_pseudogene Mus_musculus 5e-36 156
ENSMUST00000118977 Gm12647-001 processed_pseudogene Mus_musculus 6e-35 152
ENSMUST00000189783 RP24-208N6.3-001 unprocessed_pseudogene Mus_musculus 2e-34 150
ENSMUST00000119659 Gm12433-001 processed_pseudogene Mus_musculus 3e-33 147
ENSMUST00000119290 Gm13475-001 processed_pseudogene Mus_musculus 5e-26 122
ENSMUST00000120750 Gm13801-001 processed_pseudogene Mus_musculus 0.000000000000006 86

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