C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Harvey rat sarcoma viral oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000493230 HRAS-001 ENSG00000174775 9606 - 11:532242-535538 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonOvaryENST00000493230
Transcript ID Colon Ovary
ENST00000493230 4.311±0.00 8.111±4.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OR CIL_0003OR_0001 CGP 11:494512-537287
CIL_00040A CIL_00040A_0002 CGP 11:532242-554916

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 TAS MAPK cascade
GO:0000186 TAS activation of MAPKK activity
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IDA:IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 TAS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0006935 TAS chemotaxis
GO:0007050 IDA cell cycle arrest
GO:0007093 IDA mitotic cell cycle checkpoint
GO:0007165 NAS:IEA signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007265 IDA Ras protein signal transduction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008022 IPI protein C-terminus binding
GO:0008284 IDA positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009887 TAS organ morphogenesis
GO:0010629 IDA negative regulation of gene expression
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030335 IDA positive regulation of cell migration
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0034259 IDA negative regulation of Rho GTPase activity
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0043410 IDA positive regulation of MAPK cascade
GO:0045087 TAS innate immune response
GO:0045740 IDA positive regulation of DNA replication
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IDA positive regulation of JNK cascade
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0050900 TAS leukocyte migration
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090303 IDA positive regulation of wound healing
GO:0090398 IDA cellular senescence
GO:1900029 IDA positive regulation of ruffle assembly
GO:2000251 IDA positive regulation of actin cytoskeleton reorganization
GO:2000630 IDA positive regulation of miRNA metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168550 Hras-201 protein_coding Mus_musculus 0 819
ENSMUST00000124314 Hras-005 processed_transcript Mus_musculus 0 464
ENSMUST00000128993 Hras-003 retained_intron Mus_musculus 0.00000000002 75
ENSMUST00000026572 Hras-002 protein_coding Mus_musculus 0 632

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