| Transcript ID | Lung |
|---|---|
| ENST00000509490 | 9.526±0.00 |
Genome
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C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Transcript Info |
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| Description: | platelet-derived growth factor receptor, alpha polypeptide | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000509490  |
PDGFRA-008 |
ENSG00000134853 |
9606 | + |
4:54229311-54281978  |
nonsense_mediated_decay |
|
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Expression Patterns
|
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_0001CS | CIL_0001CS_0001 | CGP | 4:52872982-54295272 |
| CIL_0001CL | CIL_0001CL_0001 | CGP | 4:53377643-54295272 |
| CIL_0007R1 | CIL_0007R1_0001 | VISTA | 4:53715055-54316288 |
| CIL_0008IT | CIL_0008IT_0001 | VISTA | 4:53795831-54396629 |
| CIL_0001CO | CIL_0001CO_0001 | CGP | 4:54099523-54298247 |
| CIL_0001CJ | CIL_0001CJ_0001 | CGP | 4:54229097-54740715 |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0001553 | ISS | luteinization |
| GO:0001775 | TAS | cell activation |
| GO:0004672 | IEA | protein kinase activity |
| GO:0004713 | IEA | protein tyrosine kinase activity |
| GO:0004714 | IDA | transmembrane receptor protein tyrosine kinase activity |
| GO:0005018 | IDA | platelet-derived growth factor alpha-receptor activity |
| GO:0005021 | IDA | vascular endothelial growth factor-activated receptor activity |
| GO:0005161 | IPI | platelet-derived growth factor receptor binding |
| GO:0005515 | IPI:IEA | protein binding |
| GO:0005524 | IEA | ATP binding |
| GO:0005634 | ISS | nucleus |
| GO:0005737 | ISS | cytoplasm |
| GO:0005886 | TAS | plasma membrane |
| GO:0005887 | IDA | integral component of plasma membrane |
| GO:0006468 | IEA | protein phosphorylation |
| GO:0007173 | TAS | epidermal growth factor receptor signaling pathway |
| GO:0007204 | IMP | positive regulation of cytosolic calcium ion concentration |
| GO:0008284 | IMP | positive regulation of cell proliferation |
| GO:0008543 | TAS | fibroblast growth factor receptor signaling pathway |
| GO:0010544 | IDA | negative regulation of platelet activation |
| GO:0010863 | IMP | positive regulation of phospholipase C activity |
| GO:0014068 | TAS | positive regulation of phosphatidylinositol 3-kinase signaling |
| GO:0016020 | IDA | membrane |
| GO:0016032 | IEA | viral process |
| GO:0016772 | IEA | transferase activity, transferring phosphorus-containing groups |
| GO:0018108 | IDA | peptidyl-tyrosine phosphorylation |
| GO:0030335 | IMP | positive regulation of cell migration |
| GO:0031226 | IDA | intrinsic component of plasma membrane |
| GO:0035790 | IMP | platelet-derived growth factor receptor-alpha signaling pathway |
| GO:0038085 | IPI | vascular endothelial growth factor binding |
| GO:0038091 | IDA | positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway |
| GO:0038095 | TAS | Fc-epsilon receptor signaling pathway |
| GO:0042060 | ISS | wound healing |
| GO:0042803 | IDA | protein homodimerization activity |
| GO:0043552 | IMP | positive regulation of phosphatidylinositol 3-kinase activity |
| GO:0045087 | TAS | innate immune response |
| GO:0045740 | IDA | positive regulation of DNA replication |
| GO:0046777 | IDA | protein autophosphorylation |
| GO:0048008 | IDA | platelet-derived growth factor receptor signaling pathway |
| GO:0048011 | TAS | neurotrophin TRK receptor signaling pathway |
| GO:0048015 | IMP | phosphatidylinositol-mediated signaling |
| GO:0048146 | IDA | positive regulation of fibroblast proliferation |
| GO:0048407 | IPI | platelet-derived growth factor binding |
| GO:0048557 | ISS | embryonic digestive tract morphogenesis |
| GO:0048701 | ISS | embryonic cranial skeleton morphogenesis |
| GO:0048704 | ISS | embryonic skeletal system morphogenesis |
| GO:0050920 | IMP | regulation of chemotaxis |
| GO:0055003 | ISS | cardiac myofibril assembly |
| GO:0060326 | IMP | cell chemotaxis |
| GO:0061298 | ISS | retina vasculature development in camera-type eye |
| GO:0070374 | IMP | positive regulation of ERK1 and ERK2 cascade |
| GO:0070527 | IMP | platelet aggregation |
| GO:0072277 | ISS | metanephric glomerular capillary formation |
| GO:2000249 | TAS | regulation of actin cytoskeleton reorganization |
| GO:2000739 | IMP | regulation of mesenchymal stem cell differentiation |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENSMUST00000000476
|
Pdgfra-201 | protein_coding | Mus_musculus | 0 | 2189 |
|
ENSMUST00000168162
|
Pdgfra-202 | protein_coding | Mus_musculus | 0 | 2182 |
