C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: opioid receptor, mu 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000522555 OPRM1-019 ENSG00000112038 9606 + 6:154086507-154118969 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QK CIL_0002QK_0002 CGP 6:153004459-154246867
CIL_00055K CIL_00055K_0001 CGP 6:154010496-154356792

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001965 IDA G-protein alpha-subunit binding
GO:0004930 ISS:IEA G-protein coupled receptor activity
GO:0004979 IMP beta-endorphin receptor activity
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005783 TAS endoplasmic reticulum
GO:0005794 TAS Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007194 ISS negative regulation of adenylate cyclase activity
GO:0007200 ISS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007600 NAS sensory perception
GO:0008285 TAS negative regulation of cell proliferation
GO:0016021 IEA integral component of membrane
GO:0019233 ISS sensory perception of pain
GO:0033554 IMP cellular response to stress
GO:0038003 IEA opioid receptor signaling pathway
GO:0038047 ISS morphine receptor activity
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0045019 IDA negative regulation of nitric oxide biosynthetic process
GO:0045429 IDA positive regulation of nitric oxide biosynthetic process
GO:0048149 IMP behavioral response to ethanol
GO:0050769 ISS positive regulation of neurogenesis
GO:0051481 IDA negative regulation of cytosolic calcium ion concentration
GO:0061358 IMP negative regulation of Wnt protein secretion
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070588 ISS calcium ion transmembrane transport
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105607 Oprm1-003 protein_coding Mus_musculus 0 1146
ENSMUST00000147171 Oprm1-001 nonsense_mediated_decay Mus_musculus 0 1146
ENSMUST00000092734 Oprm1-008 protein_coding Mus_musculus 0 1118
ENSMUST00000056385 Oprm1-007 protein_coding Mus_musculus 0 1118
ENSMUST00000150374 Oprm1-005 nonsense_mediated_decay Mus_musculus 0 1118
ENSMUST00000105597 Oprm1-004 nonsense_mediated_decay Mus_musculus 0 1118
ENSMUST00000154941 Oprm1-025 nonsense_mediated_decay Mus_musculus 0 1046
ENSMUST00000144264 Oprm1-024 nonsense_mediated_decay Mus_musculus 0 1046
ENSMUST00000135502 Oprm1-027 protein_coding Mus_musculus 0 1044
ENSMUST00000105611 Oprm1-026 protein_coding Mus_musculus 0 1044
ENSMUST00000105615 Oprm1-002 protein_coding Mus_musculus 0 1044
ENSMUST00000141897 Oprm1-022 processed_transcript Mus_musculus 0 1042
ENSMUST00000105603 Oprm1-018 protein_coding Mus_musculus 0 1042
ENSMUST00000105604 Oprm1-019 protein_coding Mus_musculus 0 1042
ENSMUST00000105602 Oprm1-011 protein_coding Mus_musculus 0 1042
ENSMUST00000078634 Oprm1-016 protein_coding Mus_musculus 0 1042
ENSMUST00000000783 Oprm1-017 protein_coding Mus_musculus 0 1042
ENSMUST00000092731 Oprm1-013 protein_coding Mus_musculus 0 1042
ENSMUST00000092729 Oprm1-014 nonsense_mediated_decay Mus_musculus 0 1042
ENSMUST00000154906 Oprm1-010 protein_coding Mus_musculus 0 1042
ENSMUST00000105605 Oprm1-015 protein_coding Mus_musculus 0 1042
ENSMUST00000129954 Oprm1-012 nonsense_mediated_decay Mus_musculus 0 1042
ENSMUST00000052751 Oprm1-030 protein_coding Mus_musculus 0 1042
ENSMUST00000129221 Oprm1-023 nonsense_mediated_decay Mus_musculus 0 1042
ENSMUST00000063036 Oprm1-029 protein_coding Mus_musculus 0 1042
ENSMUST00000143875 Oprm1-006 nonsense_mediated_decay Mus_musculus 1e-25 122
ENSMUST00000148625 Oprm1-021 processed_transcript Mus_musculus 3e-21 108
ENSMUST00000152674 Oprm1-031 protein_coding Mus_musculus 4e-20 104

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