C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dematin actin binding protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000523782 DMTN-011 ENSG00000158856 9606 + 8:22054943-22082518 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000523782
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000523782 4.883±0.00 4.857±0.00 32.464±28.41 23.750±0.00 10.599±0.00 13.569±0.00 0.170±0.00 15.825±0.00 8.389±0.00 2.501±0.43 3.343±0.00 2.203±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000810 CIL_000810_0001 VISTA 8:21687877-22288944
CIL_0008ZI CIL_0008ZI_0001 VISTA 8:21743578-22344815
CIL_000812 CIL_000812_0001 VISTA 8:21749915-22350771

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 IDA:IEA actin binding
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0005884 IDA actin filament
GO:0005886 IDA plasma membrane
GO:0006461 ISS protein complex assembly
GO:0007010 TAS:IEA cytoskeleton organization
GO:0008360 IMP regulation of cell shape
GO:0010591 IMP regulation of lamellipodium assembly
GO:0010763 ISS positive regulation of fibroblast migration
GO:0010801 ISS negative regulation of peptidyl-threonine phosphorylation
GO:0010812 ISS negative regulation of cell-substrate adhesion
GO:0014731 IDA spectrin-associated cytoskeleton
GO:0015629 TAS actin cytoskeleton
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0030036 ISS actin cytoskeleton organization
GO:0030194 ISS positive regulation of blood coagulation
GO:0030507 IDA spectrin binding
GO:0031095 IDA platelet dense tubular network membrane
GO:0031253 ISS cell projection membrane
GO:0032956 IDA regulation of actin cytoskeleton organization
GO:0033137 ISS negative regulation of peptidyl-serine phosphorylation
GO:0035584 ISS calcium-mediated signaling using intracellular calcium source
GO:0035585 ISS calcium-mediated signaling using extracellular calcium source
GO:0043621 IDA protein self-association
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048821 ISS erythrocyte development
GO:0050732 ISS negative regulation of peptidyl-tyrosine phosphorylation
GO:0051017 IDA actin filament bundle assembly
GO:0051489 IMP regulation of filopodium assembly
GO:0051693 IEA actin filament capping
GO:0051895 ISS negative regulation of focal adhesion assembly
GO:0070560 ISS protein secretion by platelet
GO:0071277 ISS cellular response to calcium ion
GO:0071320 IDA cellular response to cAMP
GO:0090303 ISS positive regulation of wound healing
GO:0090315 ISS negative regulation of protein targeting to membrane
GO:0090527 ISS actin filament reorganization
GO:1900025 ISS negative regulation of substrate adhesion-dependent cell spreading
GO:1900026 ISS positive regulation of substrate adhesion-dependent cell spreading
GO:1901731 ISS positive regulation of platelet aggregation
GO:2001046 ISS positive regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110984 Dmtn-203 protein_coding Mus_musculus 0 1332
ENSMUST00000022694 Dmtn-201 protein_coding Mus_musculus 0 1332
ENSMUST00000022695 Dmtn-202 protein_coding Mus_musculus 0 1138

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