C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: cofilin 1 (non-muscle)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000525451 CFL1-001 ENSG00000172757 9606 - 11:65854675-65859415 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartENST00000525451
Transcript ID Colon Heart
ENST00000525451 10.356±0.00 3.078±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002MN CIL_0002MN_0001 CGP 11:65823022-65862026

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000281 IEA mitotic cytokinesis
GO:0001755 IEA neural crest cell migration
GO:0001842 IEA neural fold formation
GO:0002576 TAS platelet degranulation
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005886 IEA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0006606 IEA protein import into nucleus
GO:0006928 IEA cellular component movement
GO:0007010 IMP cytoskeleton organization
GO:0007015 IEA actin filament organization
GO:0007266 TAS Rho protein signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0009615 IEP response to virus
GO:0016020 IDA membrane
GO:0022604 IMP regulation of cell morphogenesis
GO:0030010 IEA establishment of cell polarity
GO:0030027 IEA lamellipodium
GO:0030030 IEA cell projection organization
GO:0030036 TAS actin cytoskeleton organization
GO:0030042 IEA actin filament depolymerization
GO:0030168 TAS platelet activation
GO:0030836 IEA positive regulation of actin filament depolymerization
GO:0030864 IEA cortical actin cytoskeleton
GO:0031252 IEA cell leading edge
GO:0031982 IDA vesicle
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043066 TAS negative regulation of apoptotic process
GO:0043200 IEA response to amino acid
GO:0045087 TAS innate immune response
GO:0045792 IEA negative regulation of cell size
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000116560 Cfl1-201 protein_coding Mus_musculus 0 1404
ENSMUST00000065243 Gm6180-201 processed_pseudogene Mus_musculus 0 721
ENSMUST00000121310 Gm8682-001 processed_pseudogene Mus_musculus 0 534
ENSMUST00000118840 Gm14933-001 processed_pseudogene Mus_musculus 0 523
ENSMUST00000122234 Gm14108-001 processed_pseudogene Mus_musculus 0 475
ENSMUST00000118997 Gm15660-001 processed_pseudogene Mus_musculus 0 401

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